Dialyte-ACDialysis Solution

Dialyte-AC Dialysis Solution is a dialysis solution manufactured by Popular Pharmaceuticals Ltd. in Bangladesh. Its active ingredient is Acetate Formulation [Hemodialysis Solution].

Indications

This solution is used for haemodialysis.

Contraindications

Known hypersensitivity to any of the ingredients of this preparation

Composition

• Calcium Chloride Dihydrate 0.5 %
• Magnessium Chloride 0.4 %
• Potassium Chloride 0.5 %
• Sodium Acetate 18.1 %
• Sodium Chloride 19.8 %

Pharmacology

Calcium chloride

is used to prevent or treat negative calcium balance. It also regulates action potential excitation threshold to facilitate nerve and muscle performance.

Potassium chloride

is a major cation of the intracellular fluid. It plays an active role in the conduction of nerve impulses in the heart, brain and skeletal muscle; contraction of cardiac skeletal and smooth muscles; maintenance of normal renal function, acid-base balance, carbohydrate metabolism and gastric secretion.

Magnessium Chloride

acts as cofactor in numerous enzymatic reactions involving protein synthesis and carbohydrate metabolism; depresses CNS, blocks peripheral neuromuscular transmission, produces anticonvulsant effects.

Sodium chloride

is the major extracellular cation. It is important in electrolyte and fluid balance, osmotic pressure control and water distribution as it restores sodium ions. It is used as a source of electrolytes and water for hydration, treatment of metabolic acidosis, priming solution in haemodialysis and treatment of hyperosmolar diabetes. It is also used as diluents for infusion of compatible drug additives.

Dosage & Administration

Recommended dose: 5 liters concentrate per dialysis or as required.

Interaction

There are no known drug interactions and none well documented.

Side Effects

Fluid and electrolyte imbalance, hypovolemia, hypotension or muscle cramping may occur.

Pregnancy & Lactation

Pregnancy Category-not Classified. FDA has not yet classified the drug into a specified pregnancy category.

Precautions & Warnings

It is used for haemodialysis purposes only.

Therapeutic Class

Haemodialysis solutions

Disclaimer: This information is for reference only. Always consult a registered physician before taking any medicine.