৳ 1.34/unit
Pack: ৳ 1.34
৳ 1.34/unit
Pack: ৳ 1.34
At a glance
Digoxin is a cardiac glycoside used for the treatment of heart failure and arrhythmias.
Indications
- Heart failure
- Atrial fibrillation with uncontrolled ventricular rate
- Acute and chronic left ventricular failure
- Congestive heart failure
Pharmacology
Digoxin is a cardiac glycoside which has positive inotropic activity characterized by an increase in the force of myocardial contraction. It also reduces the conductivity of the heart through the AV node. Digoxin also exerts direct action on vascular smooth muscle and indirect effects mediated primarily by the autonomic nervous system.
Dosage
Adult (Rapid digitalization - Atrial Fibrillation): Total loading dose 10-15 mcg/kg; give 50% initially, then 1/4 of loading dose q6-8hr twice.
Adult (Maintenance): 3.4-5.1 mcg/kg/day or 0.125-0.5 mg/day PO.
Adult (Heart Failure): 0.125-0.25 mg PO/IV daily.
Children: Age and weight-based dosing (from premature neonates to >10 years).
Side effects
Common: Nausea, vomiting, diarrhea, abdominal pain, headache, fatigue, drowsiness, confusion, delirium, hallucination, depression, arrhythmia, heart block.
Other: Visual disturbance, gynecomastia (long-term use), thrombocytopenia.
Use in pregnancy
Pregnancy Category C. Digoxin may be unsafe during pregnancy.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
May affect driving ability (dizziness, vision changes, drowsiness). Be aware of overdose symptoms (slow heartbeat, dizziness, breathing problems). Do not stop abruptly.
Overdose effects
Overdose may cause anorexia, nausea, diarrhea, visual disturbance, arrhythmia. Seek medical attention.
Storage conditions
Store in a cool and dry place. Keep out of reach of children.