৳ 22/unit
Pack: ৳ 220
৳ 22/unit
Pack: ৳ 220
At a glance
Estradiol + Progesterone is a hormone replacement therapy used for estrogen deficiency symptoms and osteoporosis prevention in postmenopausal women.
Indications
- Estrogen deficiency symptoms: Used for hot flushes, night sweats and mood changes in postmenopausal women.
- Osteoporosis prevention: Used for prevention of bone loss in postmenopausal women.
Pharmacology
Endogenous estrogens are largely responsible for the development and maintenance of the female reproductive system and secondary sexual characteristics. Estrogens act through binding to nuclear receptors in estrogen-responsive tissues. The addition of progesterone opposes the development of endometrial hyperplasia.
Dosage
Adult Dose:
- Take a single capsule orally each evening with food.
Side effects
Common Side Effects:
- Alopecia (hair loss)
- Nausea
- Abdominal pain
- Headache
- Fatigue
- Flatulence
- Dizziness
- Vaginal hemorrhage
- Vaginal discharge
- Uterine spasm
- Pelvic pain
- Breast pain
Use in pregnancy
Use in Pregnancy: Not recommended during pregnancy, labor or delivery.
Pregnancy Category: B3 — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- Blood pressure should be monitored with HRT use.
- Estrogens with or without progestins may cause fluid retention; caution in cardiac or renal dysfunction or asthma.
- Patients who develop visual disturbances, classical migraine, transient aphasia, paralysis or loss of consciousness should discontinue medication.
Overdose effects
Overdose: Overdose may be expressed by feeling sick, breast discomfort, fluid retention, bloating and vaginal bleeding. Other signs: sadness, tiredness, acne and excess hair growth.
Storage conditions
Storage: Do not store above 25 degree C. Protect from light. Keep out of reach of children.