Dobumin12.5mg/ml

Dobutamine is a medicine used for short-term treatment of cardiac decompensation (low blood pressure due to poorly functioning heart) due to disease like heart failure, cardiogenic shock, or heart attack. It increases the blood pressure by increasing the pumping capacity of the heart. Dobutamine is also used while performing stress echocardiography evaluation of the heart. It is administered under the supervision of a doctor as it requires continuous blood pressure monitoring. The dose has to be individually adjusted as per the patient's response to therapy. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. Your doctor may advise for regular monitoring of blood pressure. It may cause side effects like high blood pressure and insomnia (difficulty in sleeping). You must inform the doctor if you are suffering from any liver or kidney disease. Also, let your doctor know about all the other medications that you are using regularly. Dobutamine is a sympathomimetic agonist. It works by activating the receptors in the heart. This makes the heart pump blood with more strength and force and increases its pumping capacity in conditions such as heart failure.

• Heart failure • Low blood pressure

Dobutamine increases contractility and heart rate by stimulating ?-adrenergic receptors in the cardiac tissues.

Adult Dose: Cardiac Decompensation 0.5-1 mcg/kg/min IV continuous infusion initially, then 2-20 mcg/kg/min; not to exceed 40 mcg/kg/min Adjust according to patient's BP, heart rate, cardiac and urine output. Child Dose: Cardiac Decompensation 0.5-1 mcg/kg/min IV continuous infusion initially, then 2-20 mcg/kg/min; not to exceed 40 mcg/kg/min

Your doctor or nurse will give you this medicine. Kindly do not self administer.

If you miss a dose of Dobutamine, please consult your doctor.

Common: • High blood pressure • Insomnia (difficulty in sleeping)

[UNSAFE] Dobutamine may cause side effects which could affect your ability to drive. It is given into the vein as a drip by a healthcare professional. Your doctor may perform regular blood tests to monitor the level of sodium and potassium in the blood. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Hypersensitivity; idiopathic hypertrophic subaortic stenosis (IHSS).

Increased cardiac output when used with nitroprusside. Increased vasopressor effect of dobutamine when used with bretylium, guanethidine, oxytocic drugs or TCAs.

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Dobutamine. Please consult your doctor.

[SAFE IF PRESCRIBED] Dobutamine is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

[SAFE IF PRESCRIBED] Dobutamine is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

[SAFE IF PRESCRIBED] Dobutamine is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Dobutamine may not be needed in these patients. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Dobutamine in patients with liver disease. Please consult your doctor.

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