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At a glance

Doxophylline is used to treat and prevent symptoms of asthma and chronic obstructive pulmonary disorder (COPD). It relaxes the muscles of the air passages, widening it and making it easier to breathe.

Indications
  • Chronic obstructive pulmonary disease (COPD)
  • Asthma
Pharmacology

Doxophylline is a theophylline derivative. Its mechanism is related to inhibition of phosphodiesterase activities, resulting in bronchodilating effects. It has decreased affinity toward adenosine A1 and A2 receptors.

Dosage

Adult Dose: Tablet: 400 mg 1-3 times daily; SR tablet: 400 mg once daily. Syrup: 10 ml 2-3 times daily.

Child Dose: >12 years: 200 mg 2-3 times daily or 10 ml syrup; <12 years: 6 mg/kg/dose twice daily (up to 9 mg/kg/dose).

Side effects

Common Side Effects:

  • Upset stomach
  • Vomiting
  • Headache
  • Nausea
  • Restlessness
Use in pregnancy

Information regarding the use of Doxophylline during pregnancy is not available. Please consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Used for prevention and treatment of asthma and COPD.
  • Take at the same time each day, preferably in the evening after food.
  • Does not work immediately; keep a rescue inhaler with you.
  • Regular blood tests may be needed to monitor potassium levels and drug levels.
Overdose effects

Overdose may cause severe cardiac arrhythmias and tonic-clonic seizures. No specific antidote.

Storage conditions

Store in a dry place away from light and heat. Keep out of reach of children.

Doxophylline — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.