Duomeal
175mg+225mg/5mlOTC৳ 64.40/unit
Pack: ৳ 64.40
৳ 64.40/unit
Pack: ৳ 64.40
At a glance
Aluminium Oxide + Magnesium Hydroxide is a combination antacid used to neutralize excess stomach acid and treat hyperacidity, peptic ulcer, gastritis, and heartburn.
Indications
Hyperacidity, peptic ulcer, gastritis, heartburn, sour stomach, dyspepsia, flatulence, gastric ulcer, duodenal ulcer, stomach distension.
Pharmacology
Aluminium hydroxide neutralizes gastric HCl to form aluminium chloride salt and water and forms a protective coating over the ulcer surface to facilitate healing. Magnesium hydroxide increases peristaltic activity causing osmotic retention of fluids, resulting in bowel evacuation, and reacts with hydrochloric acid to form magnesium chloride, reducing stomach acid.
Dosage
Tablet: Chew 1-2 tablets after meals and at bedtime as needed (up to 4 times a day). Do not take more than 16 tablets in 24 hours.
Side effects
Common side effects: Diarrhea, constipation, nausea, vomiting.
With long-term use: Alkaluria (may predispose to nephrolithiasis by forming calcium phosphate precipitation), hypophosphataemia (with prolonged use).
Serious (rare): Aluminium intoxication (in chronic renal failure), hypermagnesaemia (in renal disease).
Use in pregnancy
It is advised to avoid antacid preparations in the first trimester of pregnancy.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in chronic renal impairment (risk of aluminium accumulation)
- Caution in low phosphate diets
- Avoid long-term use
- Maintain 2 hour gap with other medications (to avoid absorption interference)
- Avoid use in the first trimester of pregnancy
- Caution during lactation
Overdose effects
Overdose symptoms: severe constipation, intestinal obstruction, diarrhea, electrolyte imbalance. Treatment: drug discontinuation and symptomatic measures.
Storage conditions
Store below 30°C, protected from light and moisture. Keep out of reach of children.