Duvir90mg+400mg

Ledipasvir + Sofosbuvir is a combination of two antiviral medicines. This prescription medicine is used in the treatment of chronic hepatitis C virus (HCV) infection. It fights against the viruses to resolve the infection. Ledipasvir + Sofosbuvir should be taken in the prescribed dose and duration. It can be taken with or without food, but take it at the same time daily. It is advised not to consume more than the recommended dose. It is important to inform your doctor if you have any health conditions such as liver or kidney disease. It is harmful to consume alcohol along with this medicine, so it is advised to limit or avoid alcohol. The course of the medicine should be completed for better results. The common side effects of this medicine are tiredness and headache. You should drink plenty of fluid and eat a healthy diet to prevent or overcome the side effects. Before taking the medicine, inform your doctor if you are taking any other medicines or supplements. Ledipasvir + Sofosbuvir is a combination of two antiviral medicines: Ledipasvir and Sofosbuvir. They work by lowering the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time.

• Chronic hepatitis C virus (HCV) infection

Ledipasvir is an HCV NS5A inhibitor and Sofosbuvir is a nucleotide analog inhibitor of HCV NS5B polymerase. Ledipasvir is a potent inhibitor of HCV NS5A, a viral phosphoprotein that plays an important role in viral replication, assembly, and secretion. Sofosbuvir is a nucleotide analog inhibitor of hepatitis C virus NS5B polymerase—the key enzyme mediating HCV RNA replication. The triphosphate form of sofosbuvir (GS-461203) mimics the natural cellular uridine nucleotide and is incorporated by the HCV RNA polymerase into the elongating RNA primer strand, resulting in chain termination.

Adult Dose: Oral Hepatitis C Indicated for adults with chronic hepatitis C virus (HCV) genotypes 1, 4, 5, or 6 infection Recommended dosage: One tablet (90 mg of Ledipasvir and 400 mg of Sofosbuvir) taken once daily. Recommended treatment duration: Treatment-naive with or without cirrhosis: 12 weeks Treatment-experienced without cirrhosis: 12 weeks Treatment-experienced with cirrhosis: 24 weeks Hepatic impairment Mild, moderate, or severe: No dosage adjustment required Decompensated cirrhosis: Safety and efficacy not established Child Dose: Safety and efficacy not established Renal Dose: Renal impairment Mild or moderate: No dosage adjustment required Severe (eGFR <30 mL/min/1.73 m²) or ESRD: No dosage recommendation can be given

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ledipasvir + Sofosbuvir may be taken with or without food, but it is better to take it at a fixed time.

Common: • Tiredness • Headache

[UNSAFE] Ledipasvir + Sofosbuvir may cause side effects which could affect your ability to drive. Ledipasvir + Sofosbuvir, when taken together with other medicines for the treatment of hepatitis c infection, may produce dizziness, blurred vision and this may affect your ability to drive. Ledipasvir + Sofosbuvir is used for the treatment of chronic hepatitis C virus (HCV) infection. Take it with food, preferably at the same time everyday. You will usually need to take this medicine every day for either 12 or 24 weeks. Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time. It may cause fatigue, dizziness, and blurred vision. Don't drive or do anything requiring concentration until you know how it affects you. Ledipasvir + Sofosbuvir may cause headaches. Drink plenty of water and take a suitable painkiller. Inform your doctor if it does not go away. Your doctor may monitor your liver function and the amount of hepatitis C virus in your body regularly. Do not stop taking this medicine without your doctor’s advice.

Hypersensitivity.

Reduced therapeutic effect w/ drugs that are potent P-gp inducers in the intestine (eg rifampicin, St. John's wort, carbamazepine & phenytoin), modafinil, phenobarb/oxcarbazepine, rifabutin/rifapentine. P-gp &/or BCRP inhibitors. May result in serious symptomatic bradycardia when co-administered w/ amiodarone in combination w/ another direct acting antiviral.

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Ledipasvir + Sofosbuvir. Please consult your doctor.

[SAFE IF PRESCRIBED] Ledipasvir + Sofosbuvir is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

[SAFE IF PRESCRIBED] Ledipasvir + Sofosbuvir is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

[CAUTION] Ledipasvir + Sofosbuvir should be used with caution in patients with severe kidney disease. Dose adjustment of Ledipasvir + Sofosbuvir may be needed. Please consult your doctor. Limited information is available on use of Ledipasvir + Sofosbuvir in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease. [SAFE IF PRESCRIBED] Ledipasvir + Sofosbuvir is safe to use in patients with liver disease. No dose adjustment of Ledipasvir + Sofosbuvir is recommended.

How to treatment of HEPATITIS C VIRUS https://www.1mg.com/otc/himalaya-liv.-52-ds-tablet-otc135545One ?one tablet morning & evening after taking food , use at least 1-2 monthsUse this medicine along with your treatment I am affected from hepatitis c virus diagnosed with confirmed genotype. Meanwhile i am pregnant will hepatitis virus pass on my baby. Or i should abort Your reports are of february with no ongoin liver damage. You havnt got the quantitative analysis. Most probably you wont need to abort. But be in constant follow up of good gastroenterologist near you. How to get rid of Hepatitis C virus present inside the body which is still nonreactive ? Consult a Gastro enterologist Have chronic infection with semun c/s Ecoli Please elaborate your symptoms, history, treatment and investigations done. What is the GTT, HCB, tests in pregnancy ? These tests help to know chicness of diabetes in a pregnant mother and HCV is a hepatitis test. Suffering from Hepatitis B virus from last one week. Please suggest me. Pls consult a gastroenterologist Hepatitis c , drug suggest me salt name , popular brand in india Hello doctor , will you suggest me drug for hepatitis c you need to be examined in clinic before any opinion can be given Suffering from liver cancer and hepatitis c Dear sir homeopathy can be taken as Add-on therapy in your case which shall improve your quality of life and decrease the progression of disease. You can visit a homeopath for detailed discussion and treatment