E-Saline
OTC৳ 4.58/unit
Pack: ৳ 4.58
৳ 4.58/unit
Pack: ৳ 4.58
At a glance
Anhydrous Glucose + Potassium Chloride + Sodium Chloride + Sodium Bicarbonate (Oral Rehydration Salts) is used to prevent and treat dehydration caused by acute diarrhea. It replaces essential water and salts lost through stools and vomitus.
Indications
- Dehydration due to acute diarrhea
- Gastro-enteritis with dehydration
- Prolonged vomiting
- Burns with gastric fistula
- Pulmonary hemorrhage
- Intestinal bleeding
Pharmacology
Oral rehydration salts are given orally to prevent or treat dehydration due to acute diarrhoea. Essential water and salts are lost in stools and vomitus, and dehydration results when blood volume is decreased because of fluid loss from the extracellular fluid compartment.
Preservation of the facilitated glucose-sodium cotransport system in the small-bowel mucosa is the rationale of oral rehydration therapy. Glucose is actively absorbed in the normal intestine and carries sodium with it in about an equimolar ratio. Therefore, there is greater net absorption of an isotonic salt solution with glucose than one without it.
Potassium replacement during acute diarrhoea prevents below-normal serum concentrations of potassium, especially in children, in whom stool potassium losses are higher than in adults. Bicarbonates are effective in correcting the metabolic acidosis caused by diarrhoea and dehydration.
Dosage
Adult: 200-400 mL of prepared saline after each loose stool or vomiting.
Children (above 10 years): 200-400 mL of prepared saline after each loose stool or vomiting.
Children (2-10 years): 100-200 mL of prepared saline after each loose stool or vomiting.
Children (below 2 years): 50-100 mL (10-20 spoonful) after each loose stool or vomiting.
Special Instructions: Severe continuing diarrhoea or other critical fluid losses may need supplementation with parenteral fluids. Use with caution in patients with diabetes mellitus. Solutions containing acetate or gluconate ions should be used with caution as excess administration may result in metabolic alkalosis.
Side effects
No significant side effects at recommended dosage. Overdose may cause electrolyte imbalance.
Use in pregnancy
Safe to use during pregnancy for prevention of dehydration. Consult your doctor.
Precautions & warnings
Precautions:
- Caution in depressed renal function
- Severe continuing diarrhoea may need parenteral fluids
- Consult doctor in critical fluid losses
- Use with caution in patients with diabetes mellitus
- Solutions containing acetate or gluconate ions should be used with caution (excess may cause metabolic alkalosis)
Overdose effects
Overdose may cause electrolyte imbalance, hypernatremia, or hyperkalemia. Consult your doctor if symptoms occur.
Storage conditions
Store below 30°C in a cool, dry place. Prepared solution should be used within 24 hours. Keep out of reach of children.