৳ 402.05/unit
Pack: ৳ 402.05
৳ 402.05/unit
Pack: ৳ 402.05
At a glance
Hydroquinone is used for the treatment of melasma and other hyperpigmented skin conditions. It lightens skin and reduces dark patches and spots.
Indications
- Melasma
- Chloasma
- Freckles
- Senile lentigines
- Other melanin hyperpigmentation
Pharmacology
Hydroquinone is a topical depigmenting agent that produces a reversible depigmentation of the skin by inhibiting enzymatic oxidation of tyrosine to 3,4-dihydroxyphenylalanine and suppressing melanocyte metabolic processes. It suppresses the activity of tyrosinase, the enzyme required to make melanin.
Dosage
Adult Dose (Topical):
- Apply and rub in a thin layer preparation to affected area twice daily for hyperpigmented skin conditions
- For night-time use only (contains no sunblocking agents)
Child Dose: Safety and efficacy in children below 12 years have not been established
Side effects
Common Side Effects:
- Erythema (skin redness)
- Dry skin
- Skin burn
- Skin peeling
- Itching
Occasional: Hypersensitivity (localized contact dermatitis) - rare; discontinue medication and notify physician immediately
Use in pregnancy
Use in Pregnancy: May be unsafe; animal studies have shown harmful effects; topical hydroquinone should be used in pregnant women only when clearly indicated.
Precautions & warnings
Precautions:
- Test for skin sensitivity before using Hydroquinone (24 hours)
- Minor redness is not a contraindication, but itching, vesicle formation or excessive inflammatory response means further treatment is not advised
- Contains no sunblocking agents; use only at night or on areas covered by protective clothing
- During daytime, use sunscreens (UV-A and UV-B protective) and wear protective clothing
- If no bleaching or lightening effect after 2 months, discontinue medication
- Do not apply on broken or infected areas of skin
- Contains sodium metabisulfite which may cause serious allergic reactions in susceptible persons
Overdose effects
No systemic reactions from topical use reported; however treatment should be limited to relatively small areas; some patients may experience transient skin reddening and mild burning sensation which does not preclude treatment.
Storage conditions
Store in a cool and dry place, protected from light; keep out of reach of children.