Eposin IV100mg/5ml
Rx- Generic:
- Etoposide
- Company:
- Rainbow Traders
- Dosage form:
- Injection
- Pack size:
- Injection
৳ 560/unit
Pack: ৳ 560
At a glance
Etoposide — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Etoposide is used to treat different cancers of lung, and testicles. It is also sometimes used to treat some other kinds of cancer in both men and women. It can be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy. Etoposide is given as slow injection into veins under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effect of this medicine includes low blood platelets, vomiting, nausea, hair loss, and anemia (low number of red blood cells). If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It is important to use effective contraception to avoid getting pregnant or fathering a child during treatment. Before taking this medicine, let your doctor know if you have liver or kidney disease, or if have been on radiation therapy. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. Your doctor may check you for blood cells and liver functioning while taking this medicine. Etoposide is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them.
Indications
• Small cell lung cancer • Testicular cancer
Mechanism of action
Etoposide is a derivative of podophyllotoxin that inhibits DNA synthesis resulting in the arrest of the cell cycle. At low doses, it inhibits cells from entering cell cycle and at high doses, cells entering mitosis are lysed.
Dosage
Adult Dose: Intravenous Testicular Cancer 50-100 mg/m²/day IV on days 1-5, OR 100 mg/m²/day IV on days 1, 3, 5 Repeat q3-4week Small-Cell Lung Cancer 35 mg/m²/day IV for 4 days, OR 50 mg/m²/day IV for 5 days; repeat q3-4week Oral Small cell lung cancer Adult: Twice the IV dose, rounded to the nearest 50 mg. Renal Dose: Renal Impairment CrCl >50 mL/min: Dose adjustment not necessary CrCl 15-50 mL/min: 75% of regular dose CrCl < 15 mL/min: Not studied; consider further dose reductions
Administration
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Side effects
Common: • Anemia (low number of red blood cells) • Decreased blood cells (red cells, white cells, and platelets) • Decreased white blood cell count • Diarrhea • Hair loss • Liver damage • Low blood platelets • Nausea • Rash • Stomatitis (Inflammation of the mouth) • Vomiting
Precautions & warnings
[SAFE] Etoposide does not usually affect your ability to drive.
Contraindications
Hypersensitivity, pregnancy, lactation.
Drug interactions
Synergism with other cytotoxic drugs. Caution when admin with drugs that inhibit phosphatase activity. Cyclosporin A may reduce the clearance of etoposide.
Food interactions
[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Etoposide. Please consult your doctor.
Use in pregnancy
[CONSULT YOUR DOCTOR] Etoposide is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Use in lactation
[UNSAFE] Etoposide is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Renal / hepatic impairment
[CAUTION] Etoposide should be used with caution in patients with kidney disease. Dose adjustment of Etoposide may be needed. Please consult your doctor. Use of Etoposide is not recommended in patients with end-stage kidney disease. [CAUTION] Etoposide should be used with caution in patients with liver disease. Dose adjustment of Etoposide may be needed. Please consult your doctor. Use of Etoposide is not recommended in patients with severe liver disease.
Common questions
What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer. I seem to have lung cancer , becoz all the symptoms are same as lung cancer. I test my blood, they suggests me that it is highly probable to lung cancer. Sir what can i do now. This is in preliminary stage Do you think that lung cancer is diagnosed from blood Right lung tumour cancer in upper portion In jalgaon district which oncologist is best for lung cancer. Dr Nitin Chaudhari us best oncologist Please see the attached file Doctor U will need medicines but right now priority is treating lung cancer Medicine for cure of lung cancer Hi Need to consult to face to face , Kindly consult to Ayurvedic doctor in your area I want to know the symptoms of cancer as I am a smoker Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time. Sir my dad has stage 4 lung cancer is there any treatment for it Sir can you advice me ayurvedic is better treatment for it No ayurvedic treatment for lung cancerIn allopathy 4 types of treatment are available Lung cancer stages and symptoms and standard treatment There are 4 stages, treatment would be according to it may be chemotherapy, radiotherapy or surgery, and targeted therapy. Symptoms could be cough, chest pain dyspnea etc.