Eraxis100mg
Rx- Generic:
- Anidulafungin
- Company:
- Radiant Pharmaceuticals Ltd.
- Dosage form:
- Infusion
- Pack size:
- Infusion
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At a glance
Anidulafungin is an antifungal medication used in the treatment of severe fungal infections. It kills the fungi that cause infections by preventing them from making their protective covering.
Indications
- Candidemia
- Other forms of Candida infections (intra-abdominal abscess, peritonitis)
- Esophageal candidiasis
Dosage
| Infection Type | Adult Dose | Pediatric Dose (1 month+) |
|---|---|---|
| Candidemia & Other Candida Infections | 200 mg loading dose on Day 1, followed by 100 mg once daily (for at least 14 days after last positive culture) | 3 mg/kg (max 200 mg) loading dose on Day 1, followed by 1.5 mg/kg (max 100 mg) once daily (for at least 14 days after last positive culture) |
| Esophageal Candidiasis | 100 mg loading dose on Day 1, followed by 50 mg once daily (minimum 14 days and at least 7 days after symptom resolution) | Not approved |
Special Instructions:
- Infusion rate: Do not exceed 1.1 mg/min
- No dose adjustment needed in renal or hepatic impairment
- No dose adjustment needed based on gender, weight, ethnicity, HIV positivity, or elderly
Side effects
- Hypokalemia (decreased potassium level in blood)
- Nausea
- Vomiting
- Diarrhea
- Dyspepsia
- Abdominal pain
- Pyrexia/Fever
- Insomnia
- Hypotension
- Headache
- Anemia
- Thrombocytopenia
- Injection site reactions (pain, swelling, redness)
Precautions & warnings
Serious Precautions:
- Monitor liver function regularly - risk of abnormal liver tests, hepatitis, hepatic failure
- Anaphylaxis including shock may occur - seek immediate medical attention if allergic symptoms occur
- Infusion-related reactions (rash, urticaria, flushing, pruritus, bronchospasm, dyspnea, hypotension) - do not exceed infusion rate of 1.1 mg/min
- Not approved in pediatric patients younger than 1 month (risk of polysorbate 80 toxicity)
- Hereditary Fructose Intolerance (HFI) - check history in pediatric patients
- Consult your doctor if pregnant, planning pregnancy or breastfeeding
- Complete the full course - do not stop even if you feel better
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.