Erutic 25

• Hypertension: May be used alone or in combination with other antihypertensive agents.
• Heart Failure: Used for congestive heart failure after an acute myocardial infarction.
• Edema: Used to reduce swelling caused by fluid retention.

Adult Dose:

• Hypertension: Initial 50 mg PO qDay; may increase to 50 mg PO q12hr. Full therapeutic response may take up to four weeks.
• Heart Failure Post MI: Initial 25 mg PO qDay; may titrate to maximum of 50 mg once daily within 4 weeks as tolerated.
• Hepatic Impairment: Dose adjustment not necessary.

Renal Dose: Contraindicated if CrCl <30 mL/min or serum creatinine >2 mg/dL (males) or >1.8 mg/dL (females).

Common Side Effects:

• Dizziness
• Diarrhea
• Nausea
• Cough
• Flu-like symptoms
• Fatigue
• Increased potassium level in blood
• Increased creatinine level in blood
• Abdominal pain
• Headache

Precautions:

• Eplerenone may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
• It can make you feel dizzy for the first few days. Do not drive or do anything requiring concentration until you know how it affects you.
• It may increase the level of potassium in your blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
• Your doctor will regularly check your kidney function and the amount of potassium in your blood.
• Notify your doctor if you experience dizziness, diarrhea, vomiting, fast or irregular heartbeat, swelling in feet, or difficulty breathing.
• Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.