৳ 3.01/unit
Pack: ৳ 3.01
৳ 3.01/unit
Pack: ৳ 3.01
At a glance
Eszopiclone is a sedative-hypnotic medication used for the treatment of insomnia. It reduces sleep onset time and frequent awakening at night.
Indications
- Insomnia: Indicated for the management of insomnia, including difficulty in falling asleep, difficulty in maintaining sleep during the night, and waking up too early in the morning.
Pharmacology
Eszopiclone (S-isomer of Zopiclone) is a sedative/hypnotic. It is a non-benzodiazepine that works via interaction with GABA-receptor complexes. It is rapidly absorbed and have elimination half-life (t 1/2) of approx. 6 hours in non-elderly adults. In the elderly, half life is approx. 9 hours.
Dosage
Adult Dose:
- Insomnia (18-64 years): 2 mg immediately before bedtime; may increase to 3 mg if clinically indicated.
- Elderly (>=65 years, difficulty falling asleep): 1 mg; may increase to 2 mg if needed.
- Elderly (difficulty staying asleep): 2 mg.
- Severe hepatic impairment: Max: 2 mg daily.
Child Dose: Safety and efficacy not established.
Side effects
Common Side Effects:
- Sleepiness
- Dizziness
- Headache
- Taste change
- Dryness in mouth
- Rash
- Anxiety
- Hallucination
- Respiratory tract infection
- Viral infection
- Difficulty with coordination
Use in pregnancy
Use in Pregnancy: Category C. Animal studies have shown harmful effects on the developing baby. Should be used only if potential benefit justifies potential risk to the fetus.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- Eszopiclone may impair alertness and motor coordination; risk of morning impairment increases with dose.
- Take on an empty stomach (high-fat meal reduces absorption and effect).
- Take 30-45 minutes before bedtime and only when you have time to sleep for at least 7 hours.
- It makes you feel dizzy next morning; don't drive or do anything requiring concentration.
- Inform your doctor if sleep doesn't improve after 7-10 days.
- Stop taking and inform doctor if sleep driving or memory loss occurs.
- Inform doctor if behavioral changes, new or worsening depression or suicidal thoughts occur.
- Do not stop taking suddenly (may lead to anxiety, mood changes, restlessness).
Overdose effects
Overdose: Limited pre-marketing clinical experience. One case of overdose with up to 36 mg reported where subject fully recovered.
Storage conditions
Storage: Keep below 30 degree C temperature, away from light and moisture. Keep out of reach of children.