Eslicar 400

• Partial-Onset Seizures: Indicated for partial-onset seizures as monotherapy or adjunctive therapy.

Adult Dose:

• Initial: 400 mg PO qDay (some patients may initiate at 800 mg qDay).
• Titration & Maintenance: Increase by weekly increments of 400-600 mg based on clinical response and tolerability.
• Recommended maintenance dose: 800-1600 mg once daily.
• Monotherapy: Consider 800 mg/day if unable to tolerate 1200 mg/day.
• Adjunctive therapy: Consider 1600 mg/day if unsatisfactory response with 1200 mg/day.
• Mild-moderate hepatic impairment: No dosage adjustment required.

Renal Dose (CrCl <50 mL/min): Reduce initial, titration, and maintenance doses by 50%.

Child Dose (<18 years): Safety and efficacy not established.

Common Side Effects:

• Sleepiness
• Blurred vision
• Nausea
• Headache
• Vomiting
• Double vision
• Fatigue
• Balance disorder
• Diarrhea
• Impaired coordination
• Vertigo
• Decreased appetite
• Decreased sodium level in blood
• Dizziness

Precautions:

• Eslicarbazepine may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
• Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
• Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present.
• Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.
• It may cause a reduction in blood sodium level (hyponatremia). Your doctor may monitor your blood sodium level regularly.
• Inform your doctor if you notice skin reaction such as rash, skin peeling, and itching.
• Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.