Femoston 1/5

• Relief of menopause symptoms: Used for hot flushes, night sweats and mood changes in postmenopausal women.
• Prevention of osteoporosis: Used for reducing bone loss and fracture risk in postmenopausal women.

Femoston 1/10 and Femoston 2/10 are continuous sequential hormone replacement therapies. For initiation and continuation of treatment of postmenopausal symptoms, the lowest effective dose for the shortest duration should be used. In general, treatment should start with Femoston 1/10. Depending on the clinical response, the dosage can afterwards be adjusted to individual need.

Adult Dose:

• Femoston 1/10: 28-day cycle: first 14 days 1 estradiol tablet (1 mg) daily, next 14 days 1 estradiol + dydrogesterone tablet (1 mg + 10 mg) daily.
• Femoston 2/10: 28-day cycle: first 14 days 1 estradiol tablet (2 mg) daily, next 14 days 1 estradiol + dydrogesterone tablet (2 mg + 10 mg) daily.
• Treatment: After 28 days, start new cycle on day 29; continuous without break between packs.

Common Side Effects:

• Headache
• Nausea
• Abdominal pain
• Breast pain and tenderness
• Vaginal bleeding or spotting
• Bloating
• Mood changes
• Leg cramps

Use in Pregnancy: Not indicated during pregnancy. If pregnancy occurs, treatment should be withdrawn.

Precautions:

• HRT should only be initiated for symptoms that adversely affect quality of life.
• Annual risk-benefit assessment should be undertaken and HRT continued only if benefit outweighs risk.
• Complete personal and family medical history should be taken before initiation.
• Physical (including pelvic and breast) examination should be done.
• Periodic check-ups recommended during treatment.
• Any changes in breasts should be reported to doctor.

Overdose: Overdose may cause nausea, vomiting and withdrawal bleeding. Symptomatic treatment.

Storage: Store below 30 degree C in a cool and dry place, away from light. Keep out of reach of children.