Fexib12.5mg

Rofecoxib is a pain relieving medicine. It helps relieve pain and reduces swelling, pain and redness in various joint conditions such as osteoarthritis and rheumatoid arthritis. It is also used for the treatment of migraine and menstrual pain. Rofecoxib can be taken with or without food. The dose depends on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor and should not take more or use it for longer than recommended. The most common side effects of this medicine include flu-like symptoms, indigestion, edema, dizziness, headache, irregular heartbeat, and increased blood pressure. These are not usually serious but if you are worried, ask your doctor about ways of reducing or preventing them. You should not take this medicine if you have had a recent heart attack. Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine. Consumption of alcohol can increase the risk of getting an ulcer or bleeding. Rofecoxib is a non-steroidal anti-inflammatory drug (NSAID) called COX-2 inhibitors. It works by blocking the release of certain chemical messengers that are responsible for pain and inflammation (redness and swelling).

• Pain relief

Rofecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, and antipyretic activities in animal models. The mechanism of action of (rofecoxib) is believed to be due to inhibition of prostaglandin synthesis, via inhibition of cyclooxygenase-2 (COX-2).

Adult Dose: Oral Osteoarthritis Adult: Initially, 12.5 mg once daily. Max: 25 mg/day. Pain relief Adult: Initially, 50 mg once daily followed by daily doses of 25-50 mg. Max: 50 mg/day. Treatment duration >5days is not recommended. Rheumatoid arthritis Adult: 25 mg daily. Max: 25 mg/day. Hepatic Impairment Max: 12.5 mg/day.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rofecoxib may be taken with or without food, but it is better to take it at a fixed time.

Common: • Flu-like symptoms • Peripheral edema

[CONSULT YOUR DOCTOR] It is not known whether Rofecoxib alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Rofecoxib helps relieve pain and inflammation. It may cause fewer stomach problems as compared to other NSAIDs like Ibuprofen or Naproxen. It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you. Do not consume alcohol while on treatment with this medicine as it may cause excessive drowsiness. Regularly monitor your blood pressure while taking this medicine, particularly in the first two weeks after starting treatment. Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function. Do not take Rofecoxib if you are pregnant, planning to conceive, or breastfeeding.

Hypersensitivity. Severe renal impairment.

[UNSAFE] It is unsafe to consume alcohol with Rofecoxib.

[CONSULT YOUR DOCTOR] Rofecoxib may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Information regarding the use of Rofecoxib during breastfeeding is not available. Please consult your doctor.

[CONSULT YOUR DOCTOR] There is limited information available on the use of Rofecoxib in patients with kidney disease. Please consult your doctor. Use of Rofecoxib is not recommended in patients with severe kidney disease. [CAUTION] Rofecoxib should be used with caution in patients with liver disease. Dose adjustment of Rofecoxib may be needed. Please consult your doctor. Use of Rofecoxib is not recommended in patients with moderate to severe liver disease.

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