Flontin
0.30%Rx৳ 25.49/unit
Pack: ৳ 25.49
৳ 25.49/unit
Pack: ৳ 25.49
At a glance
Ciprofloxacin 0.3% + Hydrocortisone Acetate 1% E/E prep is a combination medicine used for the treatment of bacterial infections and inflammation of the eye and ear.
Indications
- Steroid responsive inflammatory ocular conditions
- Otitis media
- Otitis externa
- Ocular inflammation associated with infection
- Post-operative inflammation of ear and eye
- Corneal Ulcers
- Bacterial Conjunctivitis
Pharmacology
Ciprofloxacin promotes breakage of double-stranded DNA in susceptible organisms and inhibits DNA gyrase, which is essential in reproduction of bacterial DNA. Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability.
Dosage
Eye Dose (Corneal Ulcers - Adult): 2 drops every 15 minutes for first 6 hours, then 2 drops every 30 minutes for remainder of first day; 2 drops hourly on 2nd day; 2 drops every 4 hours on days 3-14. May continue after 14 days if corneal re-epithelialization has not occurred.
Eye Dose (Bacterial Conjunctivitis - Adult): 1-2 drops every 2 hours for first 2 days, then 1-2 drops every 4 hours for next 5 days.
Ear Dose (Acute Otitis Externa - Adult): 4 drops into affected ear twice daily for 7 days.
Pediatric Dose (Ear): Established for patients 6 months and older (4 drops twice daily).
Pediatric Dose (Eye): Not established.
Side effects
Common Side Effects:
- Transient ocular burning or discomfort
- Stinging
- Redness
- Itching
- Periocular/facial edema
- Foreign body sensation
- Photophobia
- Blurred vision
- Tearing
- Dryness
- Eye pain
- Dizziness (rare)
Steroid Component Side Effects: Elevated intraocular pressure, glaucoma, optic nerve damage, posterior sub-capsular cataract formation, delayed wound healing.
Use in pregnancy
[CONSULT YOUR DOCTOR] Ciprofloxacin 0.3% + Hydrocortisone Acetate 1% E/E prep may be unsafe to use during pregnancy. Pregnancy Category C. Excretion in breast milk unknown; not recommended.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Prolonged use may result in overgrowth of nonsusceptible organisms including fungi.
- Monitor intraocular pressure (risk of glaucoma and optic nerve damage).
- Patients wearing contact lenses must not use the drops during the time the lenses are worn.
- Caution during pregnancy and lactation.
- Contraindicated in herpes simplex, viral conditions, mycosis, glaucoma, and newborn babies.
Overdose effects
Information on overdosage is not available. Consult a physician if overdose is suspected.
Storage conditions
Store in a cool and dry place, away from light and out of reach of children.