oshudhkosh

Fluderm 50

Rx
Generic:
Fluconazole
Dosage form:
Tablet
Pack size:
Strip (10 Tablet)

৳ 9/unit

Pack: ৳ 90

At a glance

Fluconazole — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Fluconazole belongs to a group of medicines called antifungals. It works by stopping the growth of fungus and is used to treat infections of the mouth, throat, vagina and other parts of the body including fingernails and toenails. It kills fungi by destroying the fungal cell membrane. Fluconazole should be taken in the dose and duration as prescribed by your doctor. It should be swallowed whole and can be taken with or without food. The dosage and length of treatment will depend on the condition you are being treated for. Sometimes this will be in cycles of use and non-use. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment. Tell your doctor if the infection does not get better or if it gets worse. Avoid taking antacid treatments within one hour before or two hours after you take it. The most common side effects of this medicine include stomach pain, headache and feeling sick (nausea). You could ask your doctor about ways of preventing or reducing these effects. You should stop taking it straight away if you have any signs of an allergic reaction or of congestive heart failure. Signs of this include rash, swelling of the lips, throat or face, swallowing or breathing problems, feeling dizzy or faint and nausea. Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking it if you have ever had heart failure, a weak immune system (including HIV/AIDS), kidney problems or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver by testing your blood. This medicine may make you dizzy or have blurred vision so do not drive or operate machines until it is safe. Fluconazole is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection.

Indications

• Fungal infections

Mechanism of action

Fluconazole decreases ergosterol synthesis by interfering w/ cytochrome P450 activity, thus inhibiting cell membrane formation of susceptible fungi including B. dermatitidis, Candida spp., C. immitis, C. neoformans, Epidermophyton spp., H. capsulatum, Micosporum spp., Trichophyton spp.

Dosage

Adult Dose: Oral Oropharyngeal Candidiasis 200 mg PO on Day 1, THEN 100 mg qDay Treatment should be continued for at least 2 weeks to decrease likelihood of relapse Esophageal Candidiasis 200 mg PO on Day 1, THEN 100 mg qDay; doses up to 400 mg/day may be used based on patient’s response Treat for a minimum of 3 weeks and for at least 2 weeks following resolution of symptoms Vaginal candidiasis; Candidal balanitis Uncomplicated: 150 mg PO as a single dose Complicated: 150 mg PO q72hr for 3 doses Recurrent: 150 mg PO qDay for 10-14 days followed by 150 mg once weekly for 6 months Cutaneous candidiasis; Dermatophytosis; Pityriasis versicolor Adult: 50 mg once daily for up to 6 wk. Systemic candidiasis ; Cryptococcal infections Adult: Initially, 400 mg, followed by 200-400 mg once daily. Treatment duration is based on clinical and mycological response, but is usually at least 6-8 wk in cryptococcal meningitis. To prevent relapse after a primary course of treatment for acute cryptococcal meningitis in AIDS patients: 100-200 mg daily. Prophylaxis of fungal infections in immunocompromised patients Adult: 50-400 mg daily. Prophylaxis in patients undergoing bone marrow transplantation: The recommended daily dosage is 400 mg, once daily. Patients who are anticipated to have severe granulocytopenia (less than 500 neutrophils per cu mm) should start Fluconazole Injection, USP prophylaxis several days before the anticipated onset of neutropenia, and continue for 7 days after the neutrophil count rises above 1000 cells per cu mm. Child Dose: Child: PO 3–12 mg/kg/day, max 600 mg/day q24h Max 800–1,000 mg/day may be used for some CNS fungal infections Age Average Weight Dose/Day 1 year: 9 kg - ½ spoonful 1-2 years: 12 kg- 1 spoonful 2-3 years: 14 kg- 1½ spoonful 3-4 years: 16 kg- 2 spoonful Renal Dose: Renal impairment: Haemodialysis patients: Usual dose given after each session. CrCl (ml/min) Dosage Recommendation 50 Usual dose.

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Fluconazole may be taken with or without food, but it is better to take it at a fixed time.

Missed dose

If you miss a dose of Fluconazole, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Side effects

Common: • Headache • Nausea • Rash • Vomiting

Precautions & warnings

[UNSAFE] Fluconazole may cause side effects which could affect your ability to drive. Fluconazole may cause dizziness or seizures. This may affect your ability to drive. Your doctor has prescribed Fluconazole to cure your infection and improve symptoms. Do not skip any doses and finish the full course of treatment even if you feel better. Use a reliable method of contraception to prevent pregnancy while taking this medicine. Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain. Inform your doctor if you develop severe skin rash like blistering of the skin along with fever.

Contraindications

Hypersensitivity.

Drug interactions

May increase plasma concentrations of oral hypoglycaemics (e.g. tolbutamide, glyburide, glipizide), phenytoin, theophylline, tofacitinib, rifabutin. May increase prothrombin time w/ anticoagulants. May cause significant increase in ciclosporin levels in renal transplant patients w/ or w/o renal impairment. Rifampicin reduces fluconazole levels. May increase risk of nephrotoxicity w/ tacrolimus. May increase the effect of short-acting benzodiazepines (e.g. midazolam). Potentially Fatal: Increased risk of cardiac arrhythmias or QT prolongation w/ terfenadine, cisapride, astemizole, pimozide, quinidine, halofantrine and erythromycin.

Food interactions

[CAUTION] Caution is advised when consuming alcohol with Fluconazole. Please consult your doctor.

Use in pregnancy

[CONSULT YOUR DOCTOR] Fluconazole is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Use in lactation

[SAFE IF PRESCRIBED] Fluconazole is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Renal / hepatic impairment

[UNSAFE] Fluconazole is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor. Caution to be advised in patients with impaired renal function. [CAUTION] Fluconazole should be used with caution in patients with liver disease. Dose adjustment of Fluconazole may be needed. Please consult your doctor.

Common questions

Can I get Forcan C tablet and candid b over the counter in USA That you have to check online dear as they have different regulations than us Fungal infections in body and highly itching Take gandhak rasayan 2 tablet twice, aarogyavardhini vati 2 tablet twice, apply mahamarichyadi oil fungal infections about 4-5 year old Take gandhak rasayan 1 tablet twice, Nimbadi churan half spoon thrice, Apply Jatyadi oil on the area Medicine for fungal infections. There is hundred type of fungal infectionFrom which you sufferBetter visit clinic for proper examination Fungal infections on body & face Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks.Sertacide Cream for application twice daily for 1 month.Send pictures for better diagnosis and treatment How to treat fungal infections Stop all other applications. Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks. Sertacide Cream for application twice daily for 1 month.Tab. Fexova 180 mg (if required in case of itching) Test ? Blood sugar ( Fasting & PP) The treatment has to be complete otherwise it will be recur. Fungal infections on thigh ittching Onabet cream twice a day meanwhile visit skin specialist for proper examination and treatment I am regularly using the cream cosmelite But now due to a fungal infection i have to use a antifungal cream fungicros So So i want to know whether i can apply the cream cosmelite after fungicros Pls tell me which part of body have fungal infections

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.