৳ 1/unit
Pack: ৳ 1
৳ 1/unit
Pack: ৳ 1
At a glance
Halothane is a general anaesthetic used in major surgical procedures.
Indications
- General Anaesthesia: suitable for induction and maintenance of anaesthesia for all types of surgery and in patients of all ages
Pharmacology
When inhaled, Halothane is absorbed through the alveoli into the bloodstream. In the bloodstream, Halothane circulates through the body to the principal site of action, the brain. Here Halothane causes a progressive depression of the central nervous system, beginning with the higher centers (cerebral cortex) and spreading to the vital centers in the medulla. This depression is reversible. Approximately 80% of the inhaled Halothane is eliminated unchanged by the lungs. The remaining 20% is metabolized in the liver.
Dosage
Adult Dose (Inhalation):
- Induction: 2-4% v/v Halothane in Oxygen or Nitrous Oxide
- Maintenance: 0.5-2% v/v
Child Dose (Inhalation):
- Induction: 1.5-2% v/v
- Maintenance: 0.5-1.5% v/v
* Use as directed by the registered physician
Side effects
Common Side Effects:
- Shivering
- Vomiting
- Nausea
- High grade fever
- Decreased blood pressure
- Irregular heartbeat
- Bradycardia
- Respiratory depression
Use in pregnancy
Use in Pregnancy: May be unsafe during pregnancy. Animal studies have shown harmful effects.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- Known or suspected susceptibility to malignant hyperthermia
- Raised CSF pressure
- History of unexplained jaundice or acute hepatic damage from previous exposure to halothane
- Do not drive or operate machinery for some time after anaesthesia
- Avoid use during early pregnancy
Overdose effects
Overdose: Respiratory depression, hypotension, cardiac arrest may occur. Supportive ventilation and symptomatic treatment should be given.
Storage conditions
Storage: Store in a cool dry place, protected from light. Keep in original container.