Flutrip
500mcg+10mgRx৳ 0.71/unit
Pack: ৳ 0.71
৳ 0.71/unit
Pack: ৳ 0.71
At a glance
Fluphenazine Hydrochloride + Nortriptyline is a combination medicine used in the treatment of schizophrenia and mixed anxiety-depression.
Indications
- Schizophrenia
- Mild to moderate mixed anxiety/depression
- Emotional disturbance
- Sleep disorder
- Gastric problems
Pharmacology
Fluphenazine blocks postsynaptic dopamine D1 and D2 receptors in the mesolimbic system and decreases the release of hypothalamic and hypophyseal hormones. It reduces aggressiveness with disappearance of hallucinations and delusions. Nortriptyline is a dibenzocycloheptadiene tricyclic antidepressant that increases synaptic concentration of serotonin and norepinephrine in the CNS by blocking the neuronal reuptake of norepinephrine and serotonin.
Dosage
Adult Dose:
- 1 tablet 2 to 3 times daily.
Child Dose:
- Not recommended in children.
* Use as directed by the registered physician
Side effects
Common Side Effects:
- Dryness in mouth
- Constipation
- Weight gain
- Sleepiness
- Orthostatic hypotension
- Urinary retention
- Increased prolactin level
- Blurred vision
- Increased heart rate
- Muscle stiffness
- Restlessness
- Tremor
Rare Side Effects: Tardive dyskinesia, blood dyscrasia, malignant neuroleptic syndrome, agranulocytosis.
Use in pregnancy
Use in Pregnancy: May be unsafe during pregnancy. Animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and risks.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- Caution in glaucoma, prostate enlargement, cardiac failure and myocardial infarction.
- Caution with concurrent administration of CNS depressants.
- May impair alertness and ability to drive.
- Avoid during pregnancy and lactation.
- Do not stop suddenly (may worsen symptoms).
Overdose effects
Overdose: Overdose may cause somnolence, confusion and coma. Gastric lavage and supportive measures should be employed.
Storage conditions
Storage: Store below 30°C, away from light and moisture. Keep out of reach of children.