Fonidel2.5mg/0.5ml

• Prophylaxis of deep vein thrombosis (DVT): in patients undergoing hip fracture surgery, hip replacement surgery, knee replacement surgery or abdominal surgery.
• Treatment of DVT or acute pulmonary embolism (PE): when administered in conjunction with warfarin.

Adult Dose (DVT/Pulmonary Embolism Treatment):

• <50 kg: 5 mg SC once daily
• 50-100 kg: 7.5 mg SC once daily
• >100 kg: 10 mg SC once daily
• Administer for 5-9 days (up to 26 days in clinical trials)

Prophylaxis:

• >50 kg: 2.5 mg SC once daily for 5-9 days or up to 10 days
• Hip replacement: 11 days recommended
• Knee or hip fracture: minimum 10-14 days recommended

Renal Impairment (CrCl):

• <20: Contraindicated
• 20-50: 1.5 mg once daily

Children: Safety and efficacy not established.

* Use as directed by the registered physician

Common Side Effects:

• Bleeding
• Anemia
• Injection site bleeding, rash and pruritus
• Insomnia
• Hypokalemia
• Dizziness
• Hypotension
• Confusion
• Hematoma
• Post-operative hemorrhage

Precautions:

• Increases risk of bleeding - be careful while shaving, cutting nails or using sharp objects.
• Bleeding risk is increased in renal impairment.
• Increased risk in patients with low body weight <50 kg.
• Thrombocytopenia can occur - regular platelet count monitoring recommended.
• Do not discontinue use without consulting your doctor.