৳ 402.72/unit
Pack: ৳ 402.72
৳ 402.72/unit
Pack: ৳ 402.72
At a glance
Cefpirome is an antibiotic that fights bacteria. It is used to treat severe bacterial infections of the skin, lungs (eg. pneumonia), stomach, urinary tract, and blood.
Indications
- Bacterial infections of the skin
- Lung infections (including pneumonia)
- Stomach infections
- Urinary tract infections
- Blood infections
Pharmacology
Cefpirome is a fourth generation cephalosporin antibiotic that is bactericidal. It inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall by binding to one or more of the penicillin-binding proteins (PBPs), thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Dosage
Adult Dose (IV):
| Infection Type | Dose | Schedule |
|---|---|---|
| Susceptible infections | 1-2 g | Every 12 hours |
Renal Dose Adjustment:
| Creatinine Clearance (ml/min) | Dose | Schedule |
|---|---|---|
| Loading dose | 1-2 g | — |
| 20-50 | 0.5-1 g | Twice daily |
| 5-20 | 0.5-1 g | Once daily |
| <5 (Hemodialysis patients) | 0.5 or 1 g | Once daily + half-dose after each dialysis |
Side effects
Common Side Effects:
- Rash
- Itching
- Nausea
- Vomiting
- Headache
- Fever
- Diarrhea
- Local redness and swelling at injection site
Use in pregnancy
[CONSULT YOUR DOCTOR] Cefpirome may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Precautions & warnings
- [UNSAFE] Cefpirome may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
- Your doctor has prescribed Cefpirome to cure your infection and improve your symptoms. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
- Discontinue Cefpirome and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Avoid consuming alcohol while taking Cefpirome as it may cause increased side effects.
Overdose effects
Information on Cefpirome overdosage is not available.
Storage conditions
Store below 30°C, protected from light & moisture. Keep out of the reach of children.