Fosfen2ml

Fosphenytoin Sodium is a prescription medicine used for the treatment of epilepsy (seizures). It controls seizures by decreasing the abnormal and excessive activity of the nerve cells in the brain. Fosphenytoin Sodium is given under the supervision of a healthcare professional and should not be self administered. You should never skip any doses and finish the full course of treatment even if you feel better as stopping the medication without talking to the doctor may cause non-stop seizures and can endanger life. Be careful if you are using birth control pills as this medicine may interfere with the working of contraceptives. Fosphenytoin Sodium may cause few side effects such as vomiting, itching, impaired coordination and involuntary eye movement (nystagmus) . It may also cause dizziness and sleepiness in some people, so do not drive or do anything that requires mental focus. Additionally, you may notice some injection site reactions like redness or swelling. Most side effects wear off, but if they bother you or do not go away, tell your doctor. There may be ways of preventing or reducing these effects. Fosphenytoin Sodium is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

• Epilepsy/Seizures

Fosphenytoin is a diphosphate ester salt of phenytoin which acts as a water soluble prodrug of phenytoin. After admin, plasma esterases convert fosphenytoin to phosphate, formaldehyde, and phenytoin as the active moiety; phenytoin stabilises neuronal membranes and decreases seizure activity by increasing efflux or decreasing influx of Na ions across cell membranes in the motor cortex during generation of nerve impulses.

Adult Dose: Parenteral Adult: As phenytoin Na equivalents (PSE): (The dose, concentration in dosing solutions, and infusion rate of IV Fosphenytoin is expressed as Phenytoin Sodium equivalents (PE); (Fosphenytoin Sodium 1.5 mg equivalent to Phenytoin Sodium 1 mg) to avoid the need to perform molecular weight-based adjustments when converting between Fosphenytoin and Phenytoin Sodium doses.) Status Epilepticus: By intravenous infusion (at a rate of 100-150 mg (PE)/minute), initially 15 mg (P/E)/kg then By intramuscular injection or By intravenous infusion (at a rate of 50-100 mg (PE)/minute), 4-5 mg (P/E)/kg daily in 1-2 divided doses, Prophylaxis or treatment of seizures associated with neurosurgery or head injury: By intramuscular injection or By intravenous infusion (at a rate of 50-100 mg (PE)/minute, initially 10-15 mg (PE)/kg then 4-5 mg (PE)/kg daily (in 1-2 divided doses), Temporary substitution for oral Phenytoin: By intramuscular injection or by intravenous infusion (at a rate of 50-100 mg (PE)/minute), same dose and dosing frequency as oral Phenytoin therapy. Dose adjusted according to response and through plasma-phenytoin concentration. Elderly: Lower loading dose and/or infusion rate, and lower or less frequent maintenance dose. Hepatic impairment: Dose reduction or slower infusion may be needed. Child Dose: Parenteral As phenytoin Na equivalents (PSE): (The dose, concentration in dosing solutions, and infusion rate of IV Fosphenytoin is expressed as Phenytoin Sodium equivalents (PE); (Fosphenytoin Sodium 1.5 mg equivalent to Phenytoin Sodium 1 mg) to avoid the need to perform molecular weight-based adjustments when converting between Fosphenytoin and Phenytoin Sodium doses.) Status Epilepticus: Child >5 years: By intravenous infusion (at a rate of 2-3 mg (PE)/kg/minute), initially 15 mg (PE)/kg then By intravenous infusion (at a rate of 1-2 mg (PE)/kg/minute), 4-5 mg (PE)/kg daily in 1-4 divided doses, Prophylaxis or treatment of seizures associated with neurosurgery or head injury: Child >5 years: By intravenous infusion (at a rate of 1-2 mg (PE)/kg/minute), initially 10-15 mg (PE)/kg then 4-5 mg (PE)/kg daily in 1-4 divided doses, Temporary substitution for oral Phenytoin: Child >5 years: By intravenous infusion (at a rate of 1-2 mg (PE)/kg/minute), same dose and dosing frequency as oral Phenytoin therapy. Dose adjusted according to response and through plasma-phenytoin concentration. Renal impairment: Dose reduction or slower infusion may be needed. Hepatic impairment: Dose reduction or slower infusion may be needed. Renal Dose: Renal impairment: Dose reduction or slower infusion may be needed.

Your doctor or nurse will give you this medicine. Kindly do not self administer.

If you miss a dose of Fosphenytoin Sodium, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Vomiting • Sleepiness • Dizziness • Itching • Impaired coordination • Nystagmus (involuntary eye movement)

[UNSAFE] Fosphenytoin Sodium may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. It is given as an injection either into a vein (intravenously) or into a muscle (intramuscularly). Take your medication regularly as directed by your doctor as missing doses can trigger seizures. Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you. Some healthy tips to prevent seizures: It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you. It may increase blood sugar levels.Inform your doctor if you are taking any medicines to treat diabetes. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.

Fosphenytoin is contraindicated in patients who have demonstrated hypersensitivity to Fosphenytoin or its ingredients, or to Phenytoin or other Hydantoins. Fosphenytoin is also contraindicated in patients with sinus bradycardia, sino-atrial block, second and third degree A-V block, and Adams-Stokes syndrome.

No drugs are known to interfere with the conversion of Fosphenytoin to Phenytoin. Drugs that may increase plasma Phenytoin concentrations include: Acute alcohol intake, Amiodarone, Chloramphenicol, Chlordiazepoxide, Cimetidine, Diazepam, Dicumarol, Disulfiram, Estrogens, Ethosuximide, Fluoxetine, H2-Antagonists, Halothane, Isoniazid, Methylphenidate, Phenothiazines, Phenylbutazone, Salicylates, Succinimides, Sulfonamides, Tolbutamide, Trazodone. Drugs that may decrease plasma phenytoin concentrations include: Carbamazepine, chronic alcohol abuse, Reserpine. Drugs that may either increase or decrease plasma Phenytoin concentrations include: Phenobarbital, Valproic Acid, and Sodium Valproate. Similarly, the effects of Phenytoin on Phenobarbital, Valproic Acid and Sodium plasma Valproate concentrations are unpredictable. Potentially Fatal: May cause loss of virologic response and possible resistance to delavirdine or to the class of non-nucleoside reverse transcriptase inhibitors.

[UNSAFE] It is unsafe to consume alcohol with Fosphenytoin Sodium.

[CONSULT YOUR DOCTOR] Fosphenytoin Sodium is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

[SAFE IF PRESCRIBED] Fosphenytoin Sodium is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. Please consult your doctor.

[CAUTION] Fosphenytoin Sodium should be used with caution in patients with kidney disease. Dose adjustment of Fosphenytoin Sodium may be needed. Please consult your doctor. However, talk to your doctor if you have any underlying kidney disease. [CAUTION] Fosphenytoin Sodium should be used with caution in patients with liver disease. Dose adjustment of Fosphenytoin Sodium may be needed. Please consult your doctor.

She has problem of epilepsy from last two years Hello, epilepsy and seizures cannot be treated online without physically examining the child and detailed history. I m taking 1.5gm sodium valporate,1.5 levectram, 1gm clobezam then also seizure r their at period of weekly is there alternate treatment in Ayurveda as every time at multiplying the doses at every visit As MRI eeg every tests r normal not aware of any ayurvedic medications for epilepsy is not my specialization. However you seems to have difficult to control (intractable) seizures plz follow doctors advice deligently for ur own welfare Spondilities and severe neck pain TAB. LYRICA 75MG AT BEDTIME. AVOID USING PILLOW. ?? ???? ?????? ?? ?????? ?? ?? ??? encorate Charon 200 500 tablet use krta hu kya iska koi solution h Jisse main completely thk ho jau Epilepsy requires regular treatment with anticonvulsants like encorate chrono for at least 3 years of seizure free period after which medicines may be tapered off unless seizures reappear. At present, there are no other effective treatment options. Hi I am suffering from epilepsy from the past 1.5 years but before that I have no issues with my health the symptoms are I will get vomiting sensation from evening & heavy body pains & fits will comes only in early morning from 4 & 5 am i will get un concious for about 20 or 30 minutes & I will bite my tongue & after that I will have heavy nerve pains for a day or two from 5 days I am taking encorte 500 tablets between day & night before that I used to take homeopathy treatment Epilepsy is a central nervous system disorder (neurological disorder) in which nerve cell activity in the brain becomes disrupted, causing seizures or periods of unusual behavior, sensations and sometimes loss of consciousness. Medicines for epilepsy are initially recommended for at least 3 years of seizure free interval but may continue longer depending on recurrence. Epileptic patient needs to carry a warning card or a medical emergency bracelet with identification details, his/ her epilepsy status and what people can do if fit occurs in public place. 3-4 attack of strokes in 3 yrs nothing found in CT scan & EEG.these tests are done again after 3 months. But nothing found. Doctors prescribed me Oxetol 450 mg.doctor say course of medicine is 2-3 yrs.I drink and smoke addicted to drug I don't understand if the test show nothing then why strokes happens to me? is it stroke or epilepsy; as u are on medicine for epilepsy