oshudhkosh

Fragmin7500IU/0.3ml

Rx
Dosage form:
Injection
Pack size:
7500UI PF syringe

৳ 6,314/unit

Pack: ৳ 6,314

At a glance

Dalteparin Sodium — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Dalteparin Sodium is known as an anticoagulant and is used to prevent harmful blood clots. It stops existing clots getting any bigger and stops new ones forming in the legs, lungs, brain or heart. This can help prevent Acute coronary syndrome, Deep vein thrombosis and Pulmonary embolism. Dalteparin Sodium is injected by or under the supervision of doctor. The dose and length of treatment are based on your medical condition, your response to the medicine and what you are being treated for. It may also be based on your age and weight. It is important to keep using this medicine even if you feel no symptoms because it is preventing future harm. If you stop taking it, you could get a blood clot. While taking this medicine you should avoid doing things that increase your risk of bleeding or injury. The most common side effect of this medicine is bleeding. It can also cause injection site reaction. Remember that a severe headache could be a sign of bleeding in the brain. A severe stomach ache could be a sign of bleeding in the stomach. Bleeding can be dangerous and may not be obvious. Look out for symptoms like uncontrolled bleeding gums and inform your doctor. Before using this medicine, you should tell your doctor if you have high blood pressure, diabetes or you have had a recent stroke and you should not take it if you have any current bleeding. Some medicines should not be used with Dalteparin Sodium. Tell your doctor what else you are taking to make sure it is safe. If you have low body weight, you may be at increased risk of bleeding and drinking alcohol can increase the risk of stomach bleeding. Consult your doctor about using this medicine if you are pregnant or breastfeeding. Dalteparin Sodium is an anticoagulant that prevents the formation of harmful blood clots.

Indications

• Acute coronary syndrome • Deep vein thrombosis • Pulmonary embolism

Mechanism of action

Dalteparin sodium is a low molecular weight heparin analogue which inhibits factor Xa more than factor IIa (thrombin).

Dosage

Adult Dose: Subcutaneous Venous thromboembolism Adult: 200 U/kg daily as a single or in 2 divided doses in pregnant and high-risk patients. Max: 18,000 U/day. Patients w/ symptomatic thromboembolism and cancer: 200 U/kg once daily for 30 days, followed by 150 U/kg once daily for up to 5 mth; if chemotherapy induced thrombocytopenia develops, reduce dose to 2,500 U while platelet counts are below 100,000 cells/mm3, temporarily stop treatment if platelet counts are below 50,000 cells/mm3. Prophylaxis of venous thromboembolism during surgical procedures Adult: Moderate risk patients: 2,500 U given 1-2 hr before the procedure followed by 2,500 U once daily for 5-7 days or until the patient is fully ambulant. High risk patients: 2,500 U given 1-2 hr before and 8-12 hr after the procedure followed by 5,000 U daily. Alternatively, 5,000 U given in the evening before surgery followed by 5,000 U each subsequent evening for 5-10 days, or up to 5 wk after hip replacement surgery. Medical patients: 5,000 U once daily for 14 days or longer. Unstable angina Adult: 120 U/kg 12 hrly continued for 5-8 days w/ concomitant low-dose aspirin. Max: 10,000 U 12 hrly. For patients who require treatment longer than 8 days while awaiting revascularisation procedure: 5,000 U (7,500 U in men weighing ?70 kg and women weighing ?80 kg) 12 hrly for up to 45 days until the procedure is performed. Intravenous Prophylaxis of clotting in extracorporeal circulation in haemodialysis or haemofiltration Adult: 30-40 U/kg IV inj, followed by an IV infusion of 10-15 U/kg/hr. A single dose of 5,000 U may be given for haemodialysis or haemofiltration session lasting <4 hr. For patients at high risk of bleeding or in acute renal failure: 5-10 U/kg IV inj followed by an infusion of 4-5 U/kg/hr. Child Dose: Safety & efficacy not established Renal Dose: Renal impairment: CrCl <30 mL/min: Dosage adjustment needed based on anti-Factor Xa activity.

Administration

Your doctor or nurse will guide you how to use this medicine.

Missed dose

If you miss a dose of Dalteparin Sodium, please consult your doctor.

Side effects

Common: • Injection site reaction

Precautions & warnings

[SAFE] Dalteparin Sodium does not usually affect your ability to drive. Inform your doctor if you are also taking other medicines that increase the bleeding risk like aspirin and NSAIDs. Inform your doctor if there is bleeding from gums, nose or wounds that lasts more than 15 minutes or if blood appears in your urine, stool or vomit. Do not stop taking the medication suddenly without talking to your doctor.

Contraindications

Hypersensitivity. Active major bleeding, severe coagulation disorders; lumbar puncture; sympathetic block; brain, spinal cord, eye or ear surgery; severe hypertension.

Drug interactions

Increased risk of haemorrhage w/ other anticoagulant/antiplatelet agents (e.g. aspirin/dipyridamole, glycoprotein IIb/IIIa receptor antagonists, vit K antagonists, NSAIDs, cytostatics, dextran, thrombolytics, sulfinpyrazone, probenecid, etacrynic acid). Reduced anticoagulant effect w/ antihistamines, cardiac glycosides, tetracycline and ascorbic acid.

Food interactions

[UNSAFE] It is unsafe to consume alcohol with Dalteparin Sodium.

Use in pregnancy

[SAFE IF PRESCRIBED] Dalteparin Sodium is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Use in lactation

[SAFE IF PRESCRIBED] Dalteparin Sodium is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Dalteparin Sodium is released in small amounts in the breast milk and amounts reaching the baby are also small, which would not be expected to cause any harmful effects to the baby.

Renal / hepatic impairment

[CAUTION] Dalteparin Sodium should be used with caution in patients with severe kidney disease. Dose adjustment of Dalteparin Sodium may be needed. Please consult your doctor. [CAUTION] Dalteparin Sodium should be used with caution in patients with severe liver disease. Dose adjustment of Dalteparin Sodium may be needed. Please consult your doctor.

Common questions

She took fragmin, isn&#x27;t good at now? She can take it if indicated in her case. Your gynae will be the best judge Deep vein thrombosis , swelling nd painful in both leg. You need to take a surgical consultation Looking for a specialist in Deep vein thrombosis preferably in Kochi See a vascular surgeon In road accident head and small intestine got injured . 15 stiches on head and operation of 1 inch diameter of intestine . Now spo2 level is dropping to 70% after 1 hour of removing oxygen mask Get checked for pulmonary embolism or pneumothorax GE my self v.k tiwari mbbs md i feel the patient information above is there any blood test for diagnosed pulmonary edema and pulmonary embolism Dear Sir There is no specific blood test for diagnosing pulmonary edema and embolism Thrombosis involving both main pulmonary arteries and branches . Sir the patent has been chest pain with thrombosis pulmonary in both arteries n branch So what is the solution n treatment for this patent Need to see you in person.can meet me at medanta.call 9XXXXXX a thrombosis acute infarcts in cerebellum take medicine as advised by ur ddosctor; get bp and diabets checked Hi I my gynaecologist insisted me to take fragmin injection every 24 hrs once if I get pregnant as I have my aptt level high.Is there any side effects for this in pregnancy. How much should be taken max in pregnancy. There are no side effects as such. Your Gynae will monitor you regularly. Different docs prescribe slightly diff dosage. Your Gynae will be the best to judge

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.