৳ 5.03/unit
Pack: ৳ 5.03
৳ 5.03/unit
Pack: ৳ 5.03
At a glance
Miconazole Nitrate is an antifungal medicine used for the treatment of skin fungal infections such as athlete's foot, tinea corporis, tinea cruris, and candidal infections.
Indications
- Tinea pedis (Athlete's foot)
- Tinea corporis (Ringworm)
- Tinea cruris (Dhobie itch)
- Tinea versicolor
- Candidal infections
- Skin infections (intertrigo)
- Perianal infections
- Stomatitis angularis
- Balanoposthitis
- Otitis externa
Pharmacology
Miconazole inhibits a demethylation step in ergosterol biosynthesis. Ergosterol is the main sterol in fungi. Disruption in ergosterol production creates holes in the fungal cell membrane, allowing essential constituents to leak out. It is effective against common dermatophytes and yeasts.
Dosage
Cream Dose:
- Tinea pedis, tinea cruris, tinea corporis & cutaneous candidiasis: Twice daily (morning and evening)
- Tinea versicolor: Once daily
- Apply sparingly in intertriginous areas
- Continue for 2 weeks (tinea cruris & corporis) or 1 month (tinea pedis) after symptoms resolve
Oral Gel: Adults and children ≥2 years: 2.5 ml 4 times daily; 4-24 months: 1.25 ml 4 times daily
Side effects
Side Effects:
- Nausea and vomiting (occasionally)
- Diarrhea with long-term use
- Allergic reactions (rare)
Use in pregnancy
Use in Pregnancy: Safety information not available. Avoid if possible or weigh benefits against risks.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- For external use only (cream)
- Monitor anticoagulant effect when used with anticoagulants
- Monitor phenytoin plasma levels when used concomitantly
- Caution in pregnancy and lactation
Overdose effects
Accidental overdosage may cause vomiting and diarrhea. Symptomatic and supportive treatment.
Storage conditions
Keep in a dry place away from light and heat. Keep out of reach of children.