G Pefloxacin400mg/5ml

Pefloxacin is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, skin and soft tissues and lungs (pneumonia). It cures the infection by stopping the further growth of the causative microorganisms. Pefloxacin should be used in the dose and duration as advised by your doctor. It should be taken with food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned. You may experience nausea, headache, and dizziness as side effects of this medicine. These are usually temporary and resolve on their own, but please consult your doctor if they bother you or persist for a longer duration. Diarrhea may also occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools. You should not take this medicine if you are allergic to any of its ingredients. Rarely, some people may have a severe allergic reaction which needs urgent medical attention. Signs of this include rash, swelling of the lips, tongue or face, shortness of breath or breathing problems. Special care should be taken in people with kidney problems while taking this medicine. Pefloxacin is an antibiotic. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.

• Bacterial infections

Pefloxacin is a fluoroquinolone antibacterial that exhibits its bactericidal action by inhibition of DNA gyrase and topoisomerase IV which are needed for bacterial DNA reproduction.

Adult Dose: Oral Susceptible infections Adult: 400 mg bid. Acute uncomplicated cystitis in women; Gonococcal urethritis in men Adult: 800 mg as single dose. IV Influsion Adult: 400 mg in 100 or 250 ml of 5% dextrose slow infusion over an hour bid. Renal Dose: Renal impairment: Dose reduction may be necessary.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pefloxacin is to be taken with food.

If you miss a dose of Pefloxacin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Nausea • Diarrhea • Headache • Dizziness

[UNSAFE] Pefloxacin may cause side effects which could affect your ability to drive. Your doctor has prescribed Pefloxacin to cure your infection and improve symptoms. Do not skip any doses and finish the full course of treatment even if you feel better. Discontinue Pefloxacin and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing. Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools. Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations. Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Hypersensitivity to quinolones, children <12 yr, pregnancy, lactation.

Reduced absorption with antacids, didanosine (DDI), iron salts, pirenzepine, sucralfate, vincristine, zinc salts; increased levels with cimetidine, probenecid, theophylline; increases the levels of cyclosporine; causes seizures with foscarnet, NSAIDs, piroxicam; hypoglycemia with glimeperide; antagonistic with quercetin.

[SAFE] Consuming alcohol with Pefloxacin does not cause any harmful side effects.

[CONSULT YOUR DOCTOR] Information regarding the use of Pefloxacin during pregnancy is not available. Please consult your doctor.

[CONSULT YOUR DOCTOR] Pefloxacin is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[CONSULT YOUR DOCTOR] There is limited information available on the use of Pefloxacin in patients with kidney disease. Please consult your doctor. [CAUTION] Pefloxacin should be used with caution in patients with liver disease. Dose adjustment of Pefloxacin may be needed. Please consult your doctor.

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