৳ 51.05/unit
Pack: ৳ 51.05
৳ 51.05/unit
Pack: ৳ 51.05
At a glance
Gentamicin + Hydrocortisone Acetate is a combination ear drop used for bacterial ear infections.
Indications
- Chronic suppurative otitis media
- Otitis externa
- Prophylactic treatment of otitis externa following trauma
- Post-operative local use - in infected mastoid cavities
Pharmacology
Gentamicin is an aminoglycoside antibiotic and has a bactericidal action against many Gram-negative and some strains of Gram-positive bacteria. After actively transporting across the bacterial cell membrane, Gentamicin binds to a specific receptor protein on the 30S subunit of bacterial ribosomes, and interferes with protein synthesis. Hydrocortisone depresses formation, release, and activity of endogenous mediators of inflammation as well as modifying immune response.
Dosage
Middle Ear Infection:
- Instill 2-4 drops in the affected ear three to four times a day and at night, or more frequently if required
- Press the tragus 5 times (to facilitate penetration into the middle ear)
- Maintain position for 2 minutes
Ear Canal Infection:
- Instill 2-4 drops in the affected ear three to four times a day and at night, or more frequently if required
- Pull the outer ear lobe upward and backward (to allow drops to flow into the ear canal)
- Maintain position for 2 minutes
* Use as directed by the registered physician
Side effects
Common Side Effects:
- Ear discomfort
- Ear irritation
- Gentamicin may cause irreversible partial or total deafness when given systemically or applied topically to open wounds or damaged skin (rare)
Use in pregnancy
Use in Pregnancy: Unsafe during pregnancy. There is definite evidence of risk to the developing baby.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- Discontinue at the first appearance of any sign of local or general hypersensitivity.
- Long-term continuous therapy should be avoided (may cause overgrowth of non-susceptible organisms).
- If no improvement after one week, cultures and susceptibility tests should be performed.
- In severe infections, supplement with appropriate systemic antibiotic treatment.
Overdose effects
Overdose: Overdose is unlikely when used as directed. Excessive use may cause ear irritation.
Storage conditions
Storage: Store in a cool and dry place. Protect from light and freezing. Discard contents one month after opening.