Getease 10

• Spasticity resulting from multiple sclerosis
• Flexor spasms and concomitant pain, clonus and muscular rigidity
• Skeletal muscle spasm resulting from rheumatic disorders
• Spinal cord injuries and other spinal cord diseases
• Cerebrovascular accidents or neoplastic or degenerative brain disease

Adults and children over 10 years:

• Initial dose: 5 mg 3 times daily (with or after food), gradually increased
• Dose titration: 5 mg tid for 3 days → 10 mg tid for 3 days → 20 mg tid or until desired effect
• Maximum dose: 100 mg daily

Children under 10 years:

• Initial dose: 2.5 mg (2.5 ml) 4 times daily, gradually increased
• Maintenance dose:
  • 12 months-2 years: 10-20 mg/day
  • 2-6 years: 20-30 mg/day
  • 6-10 years: 30-60 mg/day
• Maximum: >10 years: 2.5 mg/kg/day

Elderly: Initiate with lower doses.

Renal impairment: Dose reduction may be required (approximately 5 mg/day).

• Transient drowsiness
• Daytime sedation
• Dizziness
• Weakness and fatigue
• Headache (<10%)
• Insomnia (<10%)
• Nausea (~10%)
• Constipation (<10%)
• Hypotension (<10%)
• Urinary frequency (<10%)

Rare: Euphoria, excitement, depression, confusion, hallucinations, paraesthesia, nightmares, muscle pain, tinnitus, blurred vision, epileptic seizures, respiratory depression, erectile dysfunction, rash, pruritus, weight gain, etc.

• Caution when driving or operating machinery (may cause drowsiness and dizziness)
• Avoid alcohol consumption
• Do not stop suddenly after long-term use
• Use lower doses in renal impairment (approximately 5 mg/day)
• Caution and close monitoring in patients with psychotic disorders, schizophrenia, depression, or manic disorders
• May lower seizure threshold in epilepsy patients
• Caution in patients with peptic ulcer, cerebrovascular disease, hepatic, renal, or respiratory failure
• Caution during pregnancy and lactation