oshudhkosh

Gpentin300mg

Rx
Generic:
Gabapentin
Dosage form:
Tablet
Pack size:
Tablet

৳ 16.06/unit

Pack: ৳ 16.06

At a glance

Gabapentin — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Gabapentin is a medicine used to relieve the pain caused by nerve damage (neuropathic pain) due to various conditions like diabetes, shingles (herpes zoster infection), spinal cord injury, etc. It is also used to treat certain types of seizures (fits) in combination with other medicines. Gabapentin belongs to the anti-epileptic group of medicines. You may take it with or without food, but it is important to take this medicine at the same time each day to get the most benefit. The exact dose and duration of treatment will depend on your condition and how you respond to it. Your doctor will probably start this medicine at a low dose and increase it gradually. It may take a few weeks for the medicine to work properly. Follow your doctor's instructions and continue taking it regularly until your doctor advises you to stop. Do not miss any dose, otherwise, your condition may worsen. Most people taking Gabapentin do not experience any side effects. The most common ones are feeling sleepy, dizzy, or tired (fatigue). These are usually mild and go away by themselves as your body gets used to the medicine. Most side effects are not serious and do not need medical attention. Talk to your doctor if any of the side effects persist or worry you. You should avoid drinking alcohol along with this medicine as it may lead to excessive sleepiness and dizziness. Let your doctor know right away if you develop any unusual mood changes like anxiety, agitation, depression, or thoughts about harming yourself. Before taking Gabapentin, you should tell your doctor if you have any kidney-related problems or if you are more than 65 years old. Your doctor may prescribe a different dose in such people. Women who are pregnant, breastfeeding or planning to become pregnant should also consult their doctor before using this medicine. Gabapentin is an antiepileptic medication. When given for epilepsy, it is believed to work by reducing the abnormal electrical activity in the brain, thus preventing seizures. It is also used to treat nerve pain where it blocks pain by interfering with pain signals travelling through the damaged nerves and the brain.

Indications

• Neuropathic pain • Epilepsy/Seizures

Mechanism of action

Gabapentin is structurally related to the neurotransmitter GABA but is neither a GABA agonist nor antagonist. High affinity gabapentin binding sites are located throughout the brain. These sites correspond to the presence of voltage-gated Ca channels particularly controlling the ?-2/?-1 subunit. This channel appears to be located presynaptically and may modulate the release of excitatory neurotransmitters which participate in epileptogenesis and nociception.

Dosage

Adult Dose: Partial Seizures Adjunctive therapy for partial seizures with or without secondary generalization Initial: 300 mg PO q8hr May increase up to 600 mg PO q8hr; up to 2400 mg/day administered and tolerated in clinical studies; up to 3600 mg administered for short duration and tolerated Postherpetic Neuralgia Day 1: 300 mg PO qDay Day 2: 300 mg PO q12hr Day 3: 300 mg PO q8hr Maintenance: Subsequently titrate as needed up to 600 mg PO q8hr; doses >1800 mg/day have demonstrated no additional benefit Restless legs syndrome 100-300 mg PO 2 hr before bedtime on first day; may titrate every 2 weeks until symptom relieve achieved (range 300-1800 mg/day) Diabetic Neuropathy 900 mg/day PO initially; may increase gradually q3Days to 1800-3600 mg/day Hot flashes-cancer related 200-1600 mg PO qDay to q6hr for 4-8 weeks Child Dose: Partial Seizures Adjunctive therapy for partial seizures with or without secondary generalization in patients older than 12 years of age with epilepsy; also indicated as adjunctive therapy for partial seizures in pediatric patients aged 3-12 years 12 years (initial dose): 300 mg PO q8hr; may increase up to 600 mg PO q8hr Renal Dose: Renal impairment CrCl >60 mL/min: 300-1200 mg PO TID CrCl 30-60 mL/min: 200-700 mg q12hr CrCl 15-29 mL/min: 200-700 mg qDay CrCl <15 mL/min: 100-300 mg qDay Hemodialysis (CrCl <15 mL/min): Administer supplemental dose (range 125-350 mg) posthemodialysis, after each 4 hr dialysis interval; further dose reduction should be in proportion to CrCl (eg, CrCl of 7.5 mL/min should receive one-half daily posthemodialysis dose)

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gabapentin may be taken with or without food, but it is better to take it at a fixed time.

Missed dose

If you miss a dose of Gabapentin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Side effects

Common: • Dizziness • Fatigue • Fever • Impaired coordination • Nausea • Nystagmus (involuntary eye movement) • Peripheral edema • Sleepiness • Viral infection • Vomiting

Precautions & warnings

[UNSAFE] Gabapentin may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Take it at the same time every day, preferably at bedtime, to avoid any dizziness or drowsiness during the day. Avoid taking antacids 2 hours before or after taking Gabapentin as they make it harder for your body to absorb the medicine. It may cause sleepiness. Do not drive or do anything requiring concentration until you know how it affects you. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior. Do not stop taking Gabapentin suddenly without talking to your doctor as it may increase the frequency of seizure.

Contraindications

Hypersensitivity. Lactation.

Drug interactions

May increase plasma level w/ morphine. Reduced absorption w/ antacids.

Food interactions

[UNSAFE] Gabapentin may cause excessive drowsiness with alcohol.

Use in pregnancy

[CONSULT YOUR DOCTOR] Gabapentin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Use in lactation

[SAFE IF PRESCRIBED] Gabapentin is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Baby should be monitored for excessive sleepiness and weight gain.

Renal / hepatic impairment

[CAUTION] Gabapentin should be used with caution in patients with kidney disease. Dose adjustment of Gabapentin may be needed. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Gabapentin in patients with liver disease. Please consult your doctor.

Common questions

Suggest me some ain killers for sciatic nerve pain. Tab Gabapin NT 400 one at nite I had a pain in my left thigh and was said to have meralgia parasthetica". What drug could releive this?" gabapin - NT one at nite I have pain in lower back and middle back along with right side on hip also. do mRI LS spine; tab GABAPIN NT 1 BD back pain and leg pain continues Do Mri of spine Tab Gabapin NT 400 mg once nite daily Neck pain & headache & stress plese which medicines I take tab gabapin - NT 1 bd; show to neurologist I am diabetic and have problem in lower limbs of numbness burning and stretching pain get nerve conduction done; start tab gabapin NT 1 hs Ge my self v.k tiwari m.d(cardiologist) i fill the patient information above he is suffering from modrate headache(central hemisphere cerebellum region) without any other complications all diagnosis are normal BRAIN MRI normal. my first prescription was tab flunarzine 5mg od tab Dayo od tab pantoprazole40 od. Tab diclofenac. 15 days tak he filling better but again headache complication start ho gai h.Give me proper treatment for him Please check my prescription can i give these all medicines Tab CIPLAR 10 mg od,tab gabapin 100 mg od. Tab amitor 10 mg od. Tab cyproheptadine4mg od for 30 days No need for Gabapin n cypro i have neck pain from last 2yr do MRI cervical spine; cap gabapin nt 1 od

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.