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At a glance

Generic Name: Zopiclone Dosage Form: Tablet Therapeutic Class: Miscellaneous Sedatives & Hypnotics Pharmacological Class: Cyclopyrrolone Derivative (Short-acting Hypnotic Agent) Indications: Used for the short-term treatment and symptomatic relief of insomnia characterized by difficulty falling asleep, frequent night-time awakenings, and early morning awakening. Mechanism of Action: Enhances GABA-A receptor activity in the central nervous system, producing sedative and hypnotic effects. Prescription Status: Prescription Only Medicine

Indications

Difficulty falling asleep Frequent nocturnal awakenings Early morning awakening Short-term management of insomnia

Pharmacology

Zopiclone acts on the GABA-A receptor complex in the central nervous system and enhances chloride ion channel opening, resulting in reduced neuronal activity and hypnotic effects.

Dosage

Adult Dose: Oral Short-term management of insomnia Adult: 7.5 mg at bedtime. Elderly: Initially, 3.75 mg at bedtime. Hepatic impairment: Mild to moderate: Initially 3.75 mg at bedtime. Severe: Contraindicated. Child Dose: Child: Not recommended. Renal Dose: Renal impairment: Initiate at 3.75 mg at bedtime.

Side effects

Common side effects include: Somnolence Dizziness Confusion Memory impairment Feeling of drunkenness Nightmares Anxiety or nervousness Headache Tremor Muscle weakness Dry mouth Bitter taste Nausea Constipation or diarrhoea

Use in pregnancy

[CONSULT YOUR DOCTOR] Zopiclone is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Precautions & warnings

[UNSAFE] Zopiclone may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Your doctor has prescribed Zopiclone to help you fall asleep faster and sleep for longer. It is best taken without food as a high-fat meal can reduce its absorption and effect. Take it 30 to 45 minutes before bedtime and only when you have time to sleep for at least 7 hours. It makes you feel dizzy next morning. Don't drive or do anything requiring concentration until you know how it affects you. It does not affect total sleep time. However, it reduces sleep onset time and frequent awakening at night. Never share your medication with any other person who also has a sleep problem. It may cause a bitter taste in your mouth or a dry mouth. Try sipping water and inform your doctor if it bothers you. Inform your doctor if your sleep doesn’t improve after 7 to 10 days of treatment. Stop taking medication and inform your doctor If you experience sleep driving or memory loss. Do not stop taking medication suddenly as it may lead to anxiety, mood changes, and restlessness.

Overdose effects

Overdose may cause: Severe drowsiness Confusion Coma Respiratory depression Hypotension

Storage conditions

Store at room temperature (15°C–30°C). Protect from light. Keep out of reach of children.

Zopiclone — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.