I Cap200mg

• Grave's disease
• Iodine deficiency disorders
• Hyperthyroidism
• Thyroid storm
• Preoperative reduction of vascularity of the thyroid gland
• Radiation protection against radioactive iodine
• Wound and ulcer cleansing

Adult Dose (Oral):

• Preoperative reduction of thyroid vascularity: 50-250 mg (approx 1-5 drops of solution containing 1 g/ml) tid for 10-14 days before surgery
• Radiation protection against radioactive iodine: 100-150 mg 24 hr before procedure and daily for up to 10 days after
• Thyrotoxicosis: 500 mg every 4 hr (given 1 hr after an antithyroid agent)
• Iodine deficiency disorders: Iodised oil: 400 mg iodine once yearly; Pregnant: 200 mg iodine as single dose

Child Dose (Oral):

• Preoperative reduction of thyroid vascularity: 50-250 mg tid for 10-14 days before surgery
• Radiation protection: Birth-1 month: 16 mg; 1 month-3 years: 32 mg; 3-18 years: 65 mg
• Iodine deficiency disorders: Up to 1 year: 100 mg; 1-5 years: 200 mg; >6 years: 400 mg

Side Effects:

• Hypersensitivity reactions (urticaria, angioedema, cutaneous haemorrhage, purpura, fever, arthralgia, lymphadenopathy, eosinophilia)
• Goitre
• Hypothyroidism
• Hyperthyroidism
• Iodism on prolonged use (metallic taste, increased salivation, swelling and inflammation of throat, swollen and irritated eyes, pulmonary oedema, nausea, vomiting, diarrhoea)

Potentially Fatal: Fatal periarteritis, ioderma

Precautions:

• Caution in pregnancy and lactation
• Caution in hyperkalaemia, hyperthyroidism, myotonia congenita, renal function impairment, tuberculosis, hypocomplementemic vasculitis, goiter, autoimmune thyroid disease
• Children: Repeated administration not recommended in neonates (risk of hypothyroidism)
• Caution in acute bronchitis