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At a glance

Amantadine Hydrochloride is indicated for parkinsonism, drug-induced extrapyramidal reactions, and prevention or treatment of influenza A.

Indications

Treatment of parkinsonism, drug-induced extrapyramidal reactions, and prophylaxis/treatment of influenza A virus.

Pharmacology

Enhances dopamine release, inhibits reuptake, blocks NMDA receptors, and prevents viral nucleic acid release.

Dosage

Adults: 100 mg twice daily for Parkinson's/extrapyramidal reactions. Influenza A: 200 mg/day or 100 mg twice daily.

Side effects

Nausea, dizziness, insomnia, ankle edema, livedo reticularis, anxiety, headache, dry mouth, and lethargy.

Use in pregnancy

Pregnancy Category C. Use if potential benefits outweigh risks.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings

Do not discontinue abruptly in Parkinson's patients to avoid parkinsonian crisis or delirium.

Overdose effects

May cause cardiac arrhythmias, seizures, and CNS toxicity. Supportive care and gastric lavage required.

Storage conditions

Store in a cool & dry place, protected from light, out of reach of children.

Amantadine Hydrochloride — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.