osudhkosh
New
Company•Glaxo SmithKline Pharmaceuticals Ltd

Isotrex

0.05mg/100mlRx
Generic: Isotretinoin 0.05% Topical

৳ 296.94/unit

Pack: ৳ 296.94

Gel10gm tube
Save to my medicines
Alert me on price drop

At a glance

Isotretinoin 0.05% Topical gel is used for the treatment of mild to moderate inflammatory and non-inflammatory acne vulgaris.

Indications
  • Mild to moderate inflammatory and non-inflammatory acne vulgaris
Pharmacology

Isotretinoin produces its effects through altering progress through the cell cycle, cell differentiation, survival, and apoptosis. These actions reduce sebum production, preventing the blockage of pores, and growth of acne causing bacteria. Isotretinoin induces apoptosis in sebocytes and reduces hyperkeratinization. It does not directly kill bacteria but reduces the size of sebum ducts and makes the microenvironment less hospitable to acne causing bacteria.

Dosage

Adult Dose (Topical):

  • Apply sparingly over affected area once or twice daily
  • Therapeutic effect observed within 6-8 weeks of treatment

Child Dose: Safety and efficacy not established in children

Side effects

Common Side Effects:

  • Application site reactions (burning, irritation, itching and redness)
  • Dry skin
  • Cracked lips
  • Peeling
Use in pregnancy

Use in Pregnancy: Highly unsafe during pregnancy; significant harmful effects to developing baby; contraindicated in pregnancy; associated with teratogenicity when administered systemically.

Pregnancy Category: X — always consult a doctor before taking during pregnancy.

Precautions & warnings

Precautions:

  • Isotretinoin may affect your ability to drive (night vision decreased, drowsiness, dizziness)
  • Avoid exposure to sunlight (use sun-cream or protective clothing)
  • Avoid face waxing and laser treatment (skin becomes more fragile)
  • Do not use if pregnant or breastfeeding
  • Inform doctor if excessive skin dryness or skin sensitivity occurs
  • Caution with peeling agents or abrasive cleansers
Overdose effects

Acute overdosage of Isotretinoin has not been reported; accidental ingestion could induce symptoms of hypervitaminosis A (severe headaches, nausea, vomiting, drowsiness, irritability, pruritus).

Storage conditions

Store in a cool and dry place, protected from light.

Isotretinoin 0.05% Topical — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.