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At a glance

Paracetamol IV is an analgesic and antipyretic medicine used for relief of moderate pain and fever, especially after surgery or when oral administration is not possible. It is administered as an injection by a healthcare professional for short-term use.

Indications
  • Pain relief
  • Fever reduction
  • Post-operative pain
Pharmacology

Paracetamol relieves pain by peripheral blockage of pain impulse generation and inhibition of prostaglandin synthesis in the CNS. It reduces fever by inhibiting the hypothalamic heat-regulating centre.

Dosage

Adult Dose (Intravenous):

  • >50 kg: 1g up to 4 times daily by infusion over 15 min; max 4g/day
  • 33-50 kg: 15 mg/kg body weight up to 4 times daily; max 60 mg/kg (up to 3g)/day

Pediatric Dose (Intravenous):

  • >12 years, >50 kg: 1g up to 4 times daily by infusion over 15 min; max 4g/day
  • 2-12 years (≤33 kg): 15 mg/kg body weight up to 4 times daily; max 75 mg/kg/day
  • <10 kg: 7.5 mg/kg body weight up to 4 times daily
Side effects

Common Side Effects:

  • Vomiting
  • Headache
  • Insomnia
  • Constipation
  • Itching
  • Anxiety
  • Pain at injection site
Use in pregnancy

Use in Pregnancy: Safe during pregnancy; most studies show low or no risk to the developing baby.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Does not usually affect ability to drive
  • Do not use with other paracetamol-containing products (to avoid overdose)
  • Inform doctor if you have liver disease, severe kidney disease, or alcohol abuse
  • Inform doctor if you experience nausea, weight loss, pale skin, or abdominal pain within first 24 hours (signs of overdose)
  • Long-term use may require monitoring of liver, kidney, and blood components
Overdose effects

Overdose may cause nausea, vomiting, abdominal pain, pallor, weight loss, hepatic damage. Symptoms may appear within first 24 hours. Inform doctor immediately.

Storage conditions

Store in a dry place, protected from light; keep out of reach of children.

Paracetamol IV — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.