Jasocaine-A18mcg+20mg/ml
Rx- Company:
- Jayson Pharmaceuticals Ltd.
- Dosage form:
- Injection
- Pack size:
- 50ml vial
৳ 28.32/unit
Pack: ৳ 28.32
At a glance
Adrenaline + Lidocaine Hydrochloride is a combination injection used for local anesthesia and nerve blocks. Lidocaine is an amide-type local anesthetic that blocks sodium channels in nerve cells, preventing nerve impulse conduction . Adrenaline (epinephrine) is a vasoconstrictor that constricts blood vessels at the injection site, slowing lidocaine absorption, prolonging its effect, and reducing bleeding . In Bangladesh, it is available as Jasocaine A (Jayson Pharmaceuticals), Licain A (Beacon Pharmaceuticals), G-Lidocaine (Gonoshasthaya Pharma), etc
Indications
Adult: Per ml prep contains lidocaine HCl 20 mg and epinephrine 5 mcg. Dosage depends on several factors such as route, type and extent of surgical procedure, duration of anaesthesia and patient's condition and age. Max dose of lidocaine given with epinephrine: 7 mg/kg and not >500 mg.
Dosage
Adult Dose: Epilepsy, impaired cardiac conduction, CHF, DM, closed angle glaucoma, impaired liver function (if site of admin is likely to result in high blood levels), severe renal dysfunction. Local anaesthetic effect may be reduced if injected into an inflamed or infected area. Cerebrovascular insufficiency, hyperthyroidism. Neonates, elderly, patients in poor general condition (optimise patient's condition before major block), pregnancy. Renal Dose: Lidocaine is a local anaesthetic which decreases permeability of sodium ions, blocking induction and conduction of nerve impulses. Combination with epinephrine restricts systemic spread of lidocaine, vascular absorption and its duration of local anaesthetic effect.
Side effects
Common Side Effects: • Application-site reactions (irritation, redness, itching) • Mild redness, burning, or numbness • Dizziness • Nausea • Muscle spasms • Headache • Palpitations • Local necrosis • Bradycardia • Anxiety Serious Side Effects (Rare – Consult a Doctor): • CNS toxicity (due to improper IV administration) • Medullary depression with tonic and clonic seizures • Ventricular fibrillation • Severe hypertension (including cerebral hemorrhage and pulmonary edema) • Loss of consciousness • Respiratory arrest • Sodium metabisulfite may cause anaphylactic symptoms and potentially life-threatening asthma episodes in susceptible patients.
Precautions & warnings
Local anesthesia, regional anesthesia, nerve blocks, epidural and caudal anaesthesia