৳ 9/unit
Pack: ৳ 54
৳ 9/unit
Pack: ৳ 54
At a glance
St. John's Wort is a herbal supplement used for mild to moderate depression, insomnia, seasonal affective disorder (SAD), and obsessive-compulsive disorder (OCD). It exhibits antidepressant effects by inhibiting serotonin and noradrenaline reuptake.
Indications
- Mild to moderate depression
- Insomnia
- Seasonal Affective Disorder (SAD)
- Obsessive-Compulsive Disorder (OCD)
Pharmacology
St. John's Wort inhibits the reuptake of serotonin, dopamine, noradrenaline, GABA, and L-glutamate. It inhibits MAO and COMT enzymes and up-regulates serotonin receptors. These mechanisms improve mood, reduce anxiety, and improve sleep quality.
Dosage
Adult Dose (Oral):
- 1 capsule three times daily
- Take as prescribed by a doctor
Side effects
Side Effects:
- Dry mouth
- Dizziness
- Constipation
- Diarrhea
Use in pregnancy
Use in Pregnancy: Not recommended during pregnancy; long-term safety studies lacking; consult your doctor.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution with drugs metabolized by CYP450 and drugs that lower the seizure threshold
- Caution in kidney disease
- May cause liver damage (especially in pre-existing liver conditions)
Overdose effects
Overdose may cause dry mouth, dizziness, and diarrhea; provide symptomatic treatment.
Storage conditions
Keep out of reach of children; store in a cool and dry place away from direct sunlight.