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At a glance

Hyoscine Hydro Bromide is used for the prevention and control of nausea and vomiting associated with motion sickness/travel sickness.

Indications
  • Prevention and control of nausea and vomiting associated with motion sickness/travel sickness
  • Pain due to smooth muscle spasm
Pharmacology

Hyoscine Hydrobromide is an antimuscarinic (anticholinergic) medication also known as scopolamine. It prevents motion sickness by stopping messages from the vestibular system from reaching the vomiting centre in the brain. It competitively blocks muscarinic receptors and has central and peripheral actions.

Dosage

Adult Dose (Oral):

  • Motion Sickness: 300 mcg 30 minutes before journey, then 300 mcg 6 hourly if needed; Max: 3 doses in 24 hours
  • Smooth Muscle Spasm: 20 mg 4 times daily

Child Dose (Motion Sickness):

  • Over 12 years: 300 mcg 30 min before journey, repeat 6 hourly; Max: 3 doses in 24 hours
  • 7-12 years: 1-2 tablets (Max: 2 tablets in 24 hours)
  • 4-7 years: 1 tablet (Max: 2 tablets in 24 hours)
  • 3-4 years: half tablet (Max: 1 tablet in 24 hours)
  • Under 3 years: Not recommended
Side effects

Common Side Effects:

  • Blurred vision
  • Increased heart rate
  • Dryness in mouth
  • Diarrhea
  • Dilatation of pupil
  • Difficulty with micturition
  • Dizziness
Use in pregnancy

Use in Pregnancy: May be unsafe; animal studies have shown harmful effects; not recommended during pregnancy.

Precautions & warnings

Precautions:

  • Hyoscine Hydro Bromide may decrease alertness and affect vision; do not drive or operate machinery if these symptoms occur
  • Avoid alcohol (may increase drowsiness)
  • Inform doctor if you have heart problems, thyroid problems, fever, constipation or difficulty urinating
  • Aluminium hydroxide preparations may reduce absorption
  • Effect potentiated by phenothiazines, tricyclic antidepressants or alcohol
Overdose effects

No information on overdose; do not exceed the recommended dose.

Storage conditions

Store in a cool & dry place; keep out of reach of children.

Hyoscine Hydro Bromide — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.