Lamitrin 25

Lamotrigine belongs to a group of medicines called anti-epileptics. It is used to treat two conditions, epilepsy and bipolar disorder. It works by blocking the signals in the brain that trigger epileptic seizures (fits) and in another way to prevent extreme mood swings. Lamotrigine can be used alone or in combination with other medicines. It may be taken with or without food. Your doctor will decide the correct dose for you. This may increase gradually until your condition is stable. This medicine may take several weeks to work but it is important to take it regularly to get the maximum benefit. Do not stop taking it, even if you feel fine unless your doctor advises you to. You may have more seizures, or your bipolar disorder may get worse. The most common side effects of this medicine include skin rashes, headache, nausea and vomiting, difficulty sleeping, dizziness, and feeling sleepy or drowsy. Most side effects wear off, but if they bother you or do not go away, tell your doctor. Inform your doctor immediately if you notice a rash or peeling of skin. There may be ways of preventing or reducing these effects. Long-term treatment can cause weakness in your bones (osteoporosis), increasing your risk of breaking a bone. Before taking this medicine, tell your doctor if you have kidney or liver problems, depression or suicidal thoughts. Also let your healthcare professional know about all other medications you are using as some may affect, or be affected by, this medicine, including contraceptive pills. Consult your doctor if you are pregnant or breastfeeding as the dose may need to be adjusted. You should avoid driving or anything that requires concentration if this medicine makes you drowsy or dizzy. You may need frequent blood tests to check how you are responding to this medicine. Lamotrigine is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

• Epilepsy/Seizures • Bipolar disoder

Lamotrigine inhibits voltage-sensitive sodium channels, thereby stabilising neuronal membranes and consequently inhibiting pathological release of excitatory amino acids (e.g. glutamate and aspartate). These amino acids play a role in the generation and spread of epileptic seizures.

Adult Dose: Oral Epilepsy Adult: Initially, 25 mg once daily for 2 wk followed by 50 mg once daily for 2 wk; thereafter, increase the dose by a max of 50-100 mg every 1-2 wk to usual maintenance doses of 100-200 mg daily, as a single dose or in 2 divided doses. Some patients may require up to 500 mg daily. Adjunct in epilepsy Adult: With valproate: Initially, 25 mg on alternate days for 2 wk followed by 25 mg once daily for 2 wk; thereafter, increase by a max of 25-50 mg every 1-2 wk; usual maintenance doses: 100-200 mg daily in 1-2 divided doses. With enzyme-inducing antiepileptics but not with valproate: 50 mg once daily for 2 wk followed by 50 mg bid for 2 wk; thereafter, increase by a max of 100 mg every 1-2 wk; usual maintenance doses: 200-400 mg/day in 2 divided doses; up to 700 mg/day in some patients. With oxcarbazepine but no enzyme-inducing or -inhibiting antiepileptics: 25 mg once daily for 2 wk followed by 50 mg once daily for 2 wk; thereafter increase dose by a max of 50-100 mg every 1-2 wk; usual maintenance doses: 100-200 mg daily in 1-2 divided doses; up to 500 mg daily in some patients. Bipolar disorder Adult: Monotherapy: Initially, 25 mg once daily for 2 wk followed by 50 mg once daily for 2 wk; thereafter, double the daily dose at wkly intervals to usual maintenance dose of 200 mg daily. Max dose: 200 mg/day. With valproate: Initially, 25 mg every other day for 2 wk followed by 25 mg once daily for 2 wk; thereafter, double the daily dose at wkly intervals to usual maintenance dose of 100 mg daily. With enzyme-inducing antiepileptics but not with valproate: Initially, 50 mg once daily for 2 wk followed by 100 mg daily in 2 divided doses for 2 wk; thereafter, increase in 100-mg increments wkly to usual maintenance dose of 400 mg daily in 2 divided doses. Hepatic impairment: Moderate impairment (Child-Pugh category B): Reduce dose by about 50%. Severe impairment (Child-Pugh category C): Reduce dose by about 75%. Child Dose: Oral Epilepsy Child: >12 yr: Initially, 25 mg once daily for 2 wk followed by 50 mg once daily for 2 wk; thereafter, increase the dose by a max of 50-100 mg every 1-2 wk to usual maintenance doses of 100 -200 mg daily, as a single dose or in 2 divided doses. Some patients may require up to 500 mg daily. <12 yr: Not recommended. Adjunct in epilepsy Child: With valproate: Initially, 0.15 mg/kg once daily for 2 wk followed by 0.3 mg/kg once daily for 2 wk; thereafter, increase by a max of 0.3 mg/kg every 1-2 wk to usual maintenance doses of 1-5 mg/kg once daily or in 2 divided doses. Renal Dose: Renal impairment Use caution; may consider reduce the dose in significant renal impairment

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lamotrigine may be taken with or without food, but it is better to take it at a fixed time.

If you miss a dose of Lamotrigine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Skin rash • Headache • Nausea • Vomiting • Dryness in mouth • Insomnia (difficulty in sleeping) • Sleepiness • Dizziness • Back pain • Abdominal pain • Blurred vision • Double vision • Impaired coordination • Nasal congestion (stuffy nose) • Infection

[UNSAFE] Lamotrigine may cause side effects which could affect your ability to drive. Lamotrigine can cause dizziness and double vision. This may affect your ability to drive. Take your medication regularly as directed by your doctor as missing doses can trigger seizures. Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you. Some healthy tips to prevent seizures: It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you. It may cause headaches. Drink plenty of water and take a suitable pain killer. Inform your doctor if it does not go away. It may cause skin rash. Inform your doctor immediately if you notice a rash, itching and peeling of skin. Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts. Do not stop taking the medication suddenly without talking to your doctor as it may increase the frequency of seizure.

Hypersensitivity.

Metabolism enhanced by enzyme-inducing drugs e.g. phenytoin, carbamazepine, phenobarbitone, primidone, rifampicin, ethinyloestradiol/levonorgestrel combination. Metabolism reduced by sodium valproate.

[UNSAFE] Lamotrigine may cause excessive drowsiness with alcohol.

[CONSULT YOUR DOCTOR] Lamotrigine may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Lamotrigine is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Monitor the baby for rash, sleepiness or poor sucking. Also, get the platelet count and liver function test done periodically.

[CAUTION] Lamotrigine should be used with caution in patients with kidney disease. Dose adjustment of Lamotrigine may be needed. Please consult your doctor. [CAUTION] Lamotrigine should be used with caution in patients with liver disease. Dose adjustment of Lamotrigine may be needed. Please consult your doctor.

I am suffering. from fatty liver and mild prostatic enlargements. please suggest medicine I am taking me fine for mental. Problem Medicine are Lamez of. 200, d venizep 50 and lithium 400 For prostate- consult a urologist For fatty liver- consult a gastroenterologist Rest is treatment of bipolar disorder and you need follow up with your psychiatrist. zeptol cr 300, lamez 50, gardenal 60 thease tablets are affect to men fertility ( low sperm count) What are the salt in these medication She has problem of epilepsy from last two years Hello, epilepsy and seizures cannot be treated online without physically examining the child and detailed history. ?? ???? ?????? ?? ?????? ?? ?? ??? encorate Charon 200 500 tablet use krta hu kya iska koi solution h Jisse main completely thk ho jau Epilepsy requires regular treatment with anticonvulsants like encorate chrono for at least 3 years of seizure free period after which medicines may be tapered off unless seizures reappear. At present, there are no other effective treatment options. Want discontinued eptoin tablet Father had brain stroke so doctor is giving eptoin tablet 300 mg so I want ask that can tablet can remove or dose decreased ? wil depend on any recent seizures he had; and type of stroke; pls show 2 neuro I m taking 1.5gm sodium valporate,1.5 levectram, 1gm clobezam then also seizure r their at period of weekly is there alternate treatment in Ayurveda as every time at multiplying the doses at every visit As MRI eeg every tests r normal not aware of any ayurvedic medications for epilepsy is not my specialization. However you seems to have difficult to control (intractable) seizures plz follow doctors advice deligently for ur own welfare