Largactil50mg
Rx- Generic:
- Chlorpromazine Hydrochloride
- Company:
- Synovia Pharma PLC.
- Dosage form:
- Tablet
- Pack size:
- Tablet
৳ 0.60/unit
Pack: ৳ 0.60
At a glance
Chlorpromazine Hydrochloride — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Chlorpromazine Hydrochloride is a medicine used to treat various disorders such as schizophrenia and other psychoses like paranoia (delusions and feeling extremely worried or nervous), mania (overactive behavior), anxiety, agitation, and dangerously impulsive behavior. Chlorpromazine Hydrochloride is also used for controlling intractable hiccups, feeling or being sick (nausea), and autism (learning and communication difficulties). This medicine belongs to a group of drugs known as phenothiazines, which act on the central nervous system. It alters the thoughts and elevates the mood, improving the person's ability to think, feel and behave. Chlorpromazine Hydrochloride may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms. Some common side effects of this medicine include dry mouth, abnormality of voluntary movements, urinary retention, constipation, and muscle rigidity. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine can lead to weight gain, have a healthy balanced diet and exercise regularly. Before taking this medicine, inform your doctor if you have any liver disease, thyroid or kidney disease, epilepsy, Parkinson's disease, or any heart disease. If you are diabetic, it is important to monitor your blood glucose regularly while taking this medicine. Chlorpromazine Hydrochloride is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.
Indications
• Schizophrenia
Mechanism of action
Chlorpromazine is a neuroleptic that acts by blocking the postsynaptic dopamine receptor in the mesolimbic dopaminergic system and inhibits the release of hypothalamic and hypophyseal hormones. It has antiemetic, serotonin-blocking, and weak antihistaminic properties and slight ganglion-blocking activity.
Dosage
Adult Dose: Schizophrenia, Psychotic Disorders PO: 30-75 mg/day divided q6-12hr initially; maintenance: usually 200 mg/day (up to 800 mg/day in some patients; some patients may require 1-2 g/day) IV/IM: 25 mg initially, followed PRN with 25-50 mg after 1-4 hours, then increased to maximum of 400 mg q4-6hr until patient is controlled; usual dosage 300-800 mg/day Nausea & Vomiting PO: 10-25 mg q4-6hr PRN IV/IM: 25-50 mg q4-6hr PRN Preoperative Apprehension 25-50 mg PO 2-3 hours before surgery 12.5-25 mg IM 1-2 hours before surgery Intraoperative Sedation 12.5 IM q30min or 2 mg IV q2min; total dose not to exceed 25 mg Intractable Hiccups 25-50 mg PO q6-8hr; if hiccups persist after 2-3 days of oral therapy, administer 25-50 mg IM q3-4hr; if symptoms persist, administer 25-50 mg by slow IV infusion with patient lying flat in bed; monitor BP Acute Intermittent Porphyria 25-50 mg PO q6-8hr Elderly: Initially, 1/3-½ the normal adult dose. Child Dose: Behavioral Disorders, Hyperactivity >6 months: 50-100 mg/day PO/IM; 200 mg/day or more may be necessary for older hospitalized patients; for outpatients, may administer 0.55 mg/kg q4-6hr PRN Nausea & Vomiting >6 months: 0.5-1 mg/kg PO/IM q6-8hr PRN Preoperative Apprehension >6 months: 0.55 mg/kg PO/IM 1-2 hours before surgery <6 months: Safety and efficacy not established
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Chlorpromazine Hydrochloride may be taken with or without food, but it is better to take it at a fixed time.
Side effects
Common: • Sleepiness • Orthostatic hypotension (sudden lowering of blood pressure on standing) • Dryness in mouth • Abnormality of voluntary movements • Weight gain • Increased prolactin level in blood • Urinary retention • Constipation • Muscle stiffness
Precautions & warnings
[UNSAFE] Chlorpromazine Hydrochloride may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Take it at night to avoid feeling sleepy during the day. Do not drive or do anything requiring concentration until you know how CPZ 50 Tablet affects you. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Do not drink alcohol while taking CPZ 50 Tablet as it can cause serious breathing problems. Inform your doctor if you notice involuntary muscle movements. Monitor your weight during the treatment as CPZ 50 Tablet can cause weight gain. Do not stop taking the medication suddenly without talking to your doctor.
Contraindications
Do not use in patients with known hypersensitivity to phenothiazines. Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.).
Drug interactions
Potentiation of anticholinergic effects of antiparkinson agents and TCAs may lead to an anticholinergic crisis. Additive orthostatic hypotensive effect in combination with MAOIs. Reverses antihypertensive effect of guanethidine, methyldopa and clonidine. Potentially Fatal: Additive depressant effect with sedatives, hypnotics, antihistamines, general anaesthetics, opiates and alcohol.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Chlorpromazine Hydrochloride.
Use in pregnancy
[CONSULT YOUR DOCTOR] Chlorpromazine Hydrochloride may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Chlorpromazine Hydrochloride is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. If the Chlorpromazine Hydrochloride is given, monitor the baby for excessive sleepiness during breastfeeding.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Chlorpromazine Hydrochloride is safe to use in patients with kidney disease. No dose adjustment of Chlorpromazine Hydrochloride is recommended. However, inform your doctor if you have any underlying kidney disease. A close monitoring is advisable while you are taking this medicine. [CONSULT YOUR DOCTOR] There is limited information available on the use of Chlorpromazine Hydrochloride in patients with liver disease. Please consult your doctor.
Common questions
How to treat erectile dysfunction with schizophrenia https://www.1mg.com/otc/himalaya-confido-tablet-otc90667One ?one tablet morning & evening after taking food , use at least 1-2 months Is schizophrenia a major disorder. My psychiatrist prescribed me with sizodon 10 and soltus 50 Schizophrenia is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by fear, odd experiences and distorted thought pattern. Treatment is with antipsychotic medicines which may need to continue throughout life. Coping with a mental disorder as serious as schizophrenia can be challenging, both for the person with the condition and for friends and family. Here are some ways to cope: 1. Learn about schizophrenia. Education about the disorder can help motivate the person with the disease to stick to the treatment plan. Education can help friends and family understand the disorder and be more compassionate with the person who has it. 2. Join a support group. Support groups for people with schizophrenia can help them reach out to others facing similar challenges. Support groups may also help family and friends cope. 3. Stay focused on goals. Managing schizophrenia is an ongoing process. Keeping treatment goals in mind can help the person with schizophrenia stay motivated. Help your loved one remember to take responsibility for managing the illness and working toward goals. 4. Ask about social services assistance. These services may be able to assist with affordable counselling services, job placements and other daily activities. 5. Learn relaxation and stress management. The person with schizophrenia and loved ones may benefit from stress-reduction techniques such as meditation, yoga or tai chi. Please see a psychiatrist for further guidance. My psychiatrist prescribed me with sizodon 10 and soltus 50. How serious the schizophrenia is? It not possible for me to comment upon seriousness without examining patientI need to examine you to comment on that How long I have to use shicalm plus 5mg and amistride 50 mg for shizophrenia. I can have clear thoughts without medicine I tried.Even I am trying to stop nicotine. I want to cure completely and without medicine i want to stay again with a healthy brain. Schizophrenia is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by fear, odd experiences and distorted thought pattern. Treatment is with antipsychotic medicines which may need to continue throughout life. Coping with a mental disorder as serious as schizophrenia can be challenging, both for the person with the condition and for friends and family. Here are some ways to cope: 1. Learn about schizophrenia. Education about the disorder can help motivate the person with the disease to stick to the treatment plan. Education can help friends and family understand the disorder and be more compassionate with the person who has it. 2. Join a support group. Support groups for people with schizophrenia can help them reach out to others facing similar challenges. Support groups may also help family and friends cope. 3. Stay focused on goals. Managing schizophrenia is an ongoing process. Keeping treatment goals in mind can help the person with schizophrenia stay motivated. Help your loved one remember to take responsibility for managing the illness and working toward goals. 4. Ask about social services assistance. These services may be able to assist with affordable counselling services, job placements and other daily activities. 5. Learn relaxation and stress management. The person with schizophrenia and loved ones may benefit from stress-reduction techniques such as meditation, yoga or tai chi. Please see a psychiatrist for further guidance. VIGORA FORCE 50 MG/30 MG TABLET Hi kindly consult to allopathic doctor as I am an Ayurveda doctor Thyroid problem starting eltroxin 50 mcg tablet Hows thyroid level now Suffering Schizophrnia from last 20+ years. Is cure able ? We are here to helpSchizophrenia is chronic disorderSymptoms can be stopped from expressingCure is difficult word to say in schizophrenia Mk tablet 50 what are the side effects Please mention content of tablet