৳ 1.25/unit
Pack: ৳ 1.25
৳ 1.25/unit
Pack: ৳ 1.25
At a glance
Sennosides (Senna) are plant-derived laxatives used for constipation and bowel evacuation. They increase intestinal motility through the release of active anthraquinones by colonic bacteria.
Indications
- Constipation
- Bowel evacuation (pre-procedure)
Pharmacology
Sennosides are converted by colonic bacteria into active anthraquinones, which stimulate intestinal muscle contractions and increase intestinal motility. They increase water and electrolyte secretion in the large intestine, softening stool and facilitating bowel movements.
Dosage
Adult Dose (Oral):
- Constipation: 15-30 mg (as total sennosides) 1-2 times daily
- Bowel evacuation: 105-157.5 mg of sennosides on the day before procedure (as liquid preparation)
Pediatric Dose (Oral):
- 2-6 years: 3.75-7.5 mg once daily in the morning
- 6-12 years: 7.5-15 mg once daily at night or in the morning
- >12 years: 15-30 mg at bedtime
Side effects
Side Effects:
- Mild abdominal discomfort (colic and cramps)
- Diarrhea
- Prolonged use: Hypokalemia and atonic colon
- Chronic use: Reversible melanosis coli
Use in pregnancy
Use in Pregnancy: Adequate information not available; use short-term under medical supervision; consult your doctor.
Pregnancy Category: A — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Do not use in inflammatory bowel disease
- Avoid prolonged use (dependence and electrolyte imbalance)
- Do not use in undiagnosed abdominal pain
Overdose effects
Overdose may cause severe diarrhea and electrolyte imbalance; consult your doctor.
Storage conditions
Store in a cool and dry place, protected from light; keep out of reach of children.