Leptal 300

Oxcarbazepine is a prescription medicine used to treat and prevent epilepsy (seizures). However, it cannot cure epilepsy and will only work to prevent seizures for as long as you continue to take the medicine. Oxcarbazepine may be used alone or in combination with other medicines. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. It may be increased gradually. You can take this medicine with or without food but take it at the same time each day to get the most benefit. It usually takes a couple of weeks to work. It is important to take this medicine regularly and for as long as you are advised, even if you feel well. Missing doses may trigger seizures and, if you stop, your condition may get worse. It should never be stopped suddenly. The most common side effects of this medicine include nausea, vomiting, feeling dizzy, tired or drowsy, and unsteadiness. Most of these are not serious. Keep taking the medicine but talk to your doctor if these side effects bother you or do not go away. However, if you notice a skin rash or redness, tell your doctor straight away. It could develop into a life-threatening skin condition called Stevens-Johnson syndrome. Long-term treatment with this medicine can cause osteoporosis (reduced bone mass) and increase your risk of breaking a bone. Anticonvulsants like this medicine may cause suicidal thoughts and behaviors. If your mood becomes depressed, tell your doctor. This medicine may not be suitable for everybody. Before using it, tell your doctor if you have ever had heart problems, kidney or liver disease, difficulty urinating, depression or suicidal thoughts. Many other medicines can interfere with it and some should not be taken together so tell your doctor all the medicines you are taking to make sure it is safe. If you are pregnant, do not start or stop taking this medicine without asking your doctor. Drinking alcohol should be avoided as it can increase some of the side effects and can also increase your risk of seizures. You may need frequent blood tests to help your doctor make sure you are taking the right dose both before you start and while you are using it. Oxcarbazepine is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

• Epilepsy/Seizures

Oxcarbazepine blocks voltage-sensitive sodium channels, which inhibits repetitive firing, stabilises hyperexcited neuronal membranes and decreases release of synaptic impulses. These effects may prevent the spread of epileptic seizures.

Adult Dose: Oral Partial seizures Adult: Adjunctive treatment 300 mg PO q12hr initially; may increase at weekly intervals by 600 mg/day up to 1200 mg/day Monotherapy (if converting from other AED) Initial: 300 mg PO q12hr; increase by 600 mg/day qWeek up to 2400 mg/day Reduce and withdraw concomitant antiepileptic drugs (AEDs) over 3-6 weeks while reaching maximum oxcarbazepine dose in 2-4 weeks Monotherapy (if AED naive) Initial: 300 mg PO q12hr; increase by 300 mg/day q3Day to 1200 mg/day divided q12hr Diabetic Neuropathy 150-300 mg/day PO initially; may increase to 900-1200 mg/day (general recommendation) Neuralgia/Neuropathy 300 mg PO q8-12hr initially; may adjust dose to 400-2000 mg divided q8-12hr (maximum tolerated or effective dose) Hepatic impairment Mild to moderate: No dose adjustment required Severe: Unknown if dosage adjustment necessary Child Dose: Partial Seizures (Adjunctive Treatment) (age 2-4 years) Initial: 8-10 mg/kg/day PO divided q12hr; not to exceed 600 mg/day 39 kg: 900 mg PO q12hr Partial Seizures (Monotherapy) (age 4-16 years) AED: Initial, 8-10 mg/kg/day PO divided q12hr; may increase qWeek by maximum increment of 10 mg/kg/day AED-naive: Initial 8-10 mg/kg/day PO divided q12hr; may increase q3Days by 5 mg/kg/day Target maintenance: Weight-based dosing may be as high as 2100 mg/day for >60 kg 20-24.99 kg: 600-900 mg/day 25-34.99 kg: 900-1200 mg/day 35-44.99 kg: 900-1500 mg/day 45-49.99 kg: 1200-1500 mg/day 50-59.99 kg: 1200-1800 mg/day 60-69.99 kg: 1200-2100 mg/day 70 kg: 1500-2100 mg/day Renal Dose: Renal impairment CrCl <30 mL/min: Decrease initial dose by 50%, titrate up slowly

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Oxcarbazepine may be taken with or without food, but it is better to take it at a fixed time.

If you miss a dose of Oxcarbazepine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Headache • Nausea • Vomiting • Double vision • Fatigue • Dizziness • Impaired coordination • Nystagmus (involuntary eye movement) • Tremor • Abnormal vision • Altered walking • Sleepiness

[UNSAFE] Oxcarbazepine may cause side effects which could affect your ability to drive. Oxcarbazepine may make you feel sleepy or dizzy, or may cause blurred vision, lack of muscle coordination, especially when starting treatment or increasing the dose. This may affect your driving ability. Take your medication regularly as directed by your doctor as missing doses can trigger seizures. Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you. Some healthy tips to prevent seizures: It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you. It may increase the risk of low sodium levels in the blood. Inform your doctor if you develop difficulty concentrating, memory problems, confusion, weakness, and unsteadiness. Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts. Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Hypersensitivity. Lactation.

Reduced serum levels with carbamazepine, phenobarbitone, phenytoin, valproic acid. May reduce levels/effects of CYP3A4 substrates (e.g. benzodiazepines, calcium channel blockers, clarithromycin, ciclosporin, erythromycin, oestrogens, mirtazapine, nateglinide, nefazodone, nevirapine, protease inhibitors, tacrolimus, venlafaxine). May reduce efficacy of oral contraceptives. May reduce levels/effects of maraviroc. May increase levels of phenobarbitone, phenytoin.

[UNSAFE] Oxcarbazepine may cause excessive drowsiness with alcohol.

[CONSULT YOUR DOCTOR] Oxcarbazepine may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Oxcarbazepine is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Baby should be monitored for excessive sleepiness and weight gain.

[CAUTION] Oxcarbazepine should be used with caution in patients with kidney disease. Dose adjustment of Oxcarbazepine may be needed. Please consult your doctor. [CAUTION] Oxcarbazepine should be used with caution in patients with severe liver disease. Dose adjustment of Oxcarbazepine may be needed. Please consult your doctor. Dose adjustment is not recommended in patients with mild to moderate liver disease.

I consume Lobazam 5 Mg once a day and Oxetol 300 Mg twice a day on doctors prescriptions. I have a desk job involving a lot of computer /Desktop time And recently I have found difficulty remembering things along with a form of Attention defectiveness and heavy anxiety. Not only that my Seizures still occur though once or twice in a span of 2 to 3 months when even I am anxious or excited. Could you kindly help me? Is this a normal side effect of the drug if yes how can I counter it as this is affecting my work life. oxetol canb be incrsed ; talk to ur I have bipolar depression . I don&#x27;t enjoy my life anymore . Medicines are having no effect on my body. Start tab oxetol 150 mg TDS I m 41 years n in to telecom profession. I m facing nerve pain (left or right arm, legs etc) from last few months. Pain persist for few second and then goes off but it happes atleast 2 to 6 times a day. Please suggest Tab oxetol 150 mg bd My MRI reports shows nothing but I have strokes attack comes 4 times in 3 yrs I am on Oxetol 450 mg twice q day oxetol is for fits not for stroke Can i use replacement for Vinlep150 u can try oxetol or oxcarb strong pain in right jaw below tooth. pain is like electric shock and very intense. at stable no pain. pain strate while movement in mouth but random in nature. Get Mri brain Start tab oxetol 150 mg TDS my mother Struggled this problem around 14 years, how to resolve -when ever she saw his husband,she think- he has affair with another women. 2) she(mother) hit---his husband every time(stick). 3)she(Mother) start the gas stove and injury some times 4)In home she(mother) daily hit the wall in his leg. we are using olan 10 mg table 2002 to till date.when ever we are using this tables she(mother attitude fine) attitude fine. when ever we stop this medic ion --same problem repeated. Continue it Add tab oxetol. 150 mg thrice a day Review with psychiatrist Sir i am primary generalised epilepsy patient and using oxetol 300mg tablets of sun pharma from 3years. Now in 1mg app oxetol tablets of lupin pharma are available which are relatively very cheaper than sun pharma tabs. Can i use them? Pls give me suggestion sir/madam yes sure as long is adviced by Neuro Physicianor u should meet one neuro Physician