Linamide 25
Rx- Generic:
- Lenalidomide
- Company:
- Beacon Pharmaceuticals PLC
- Dosage form:
- Capsule
- Pack size:
- Strip (7 Capsule)
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৳ 400/unit
Pack: ৳ 2,800
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- ৳ 400
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At a glance
Lenalidomide is used for the treatment of multiple myeloma, myelodysplastic syndromes (MDS), mantle cell lymphoma (MCL), follicular lymphoma (FL), and marginal zone lymphoma (MZL). It has immunomodulatory, antiangiogenic, and antineoplastic properties.
Indications
- Multiple myeloma (in combination with Dexamethasone; maintenance therapy after auto-HSCT)
- Myelodysplastic syndromes (MDS) - transfusion-dependent anemia with deletion 5q cytogenetic abnormality
- Mantle cell lymphoma (MCL) - relapsed or progressed after 2 prior therapies including Bortezomib
- Follicular lymphoma (FL) - in combination with Rituximab for previously treated patients
- Marginal zone lymphoma (MZL) - in combination with Rituximab for previously treated patients
Dosage
Multiple Myeloma: 25 mg PO daily, Days 1-21 (28-day cycles) + Dexamethasone
MDS: 10 mg PO daily
MCL: 25 mg/day, Days 1-21 (28-day cycles)
FL/MZL: 20 mg PO daily, Days 1-21 + Rituximab
Renal Impairment: Dose adjustment needed in moderate-severe cases
Side effects
Common Side Effects:
- Headache, weakness, nausea, rash, dizziness, drowsiness
- Edema, loss of appetite, decreased white blood cell count, decreased calcium, weight gain
- Muscle weakness, fatigue, fever, anxiety, blood clots, dry skin
- Weight loss, confusion, decreased neutrophils, neuropathy, constipation, tremor
Precautions & warnings
- Embryo-fetal toxicity - absolutely contraindicated in pregnancy
- Hematologic toxicity - monitor CBC regularly
- Venous and arterial thromboembolism - thromboprophylaxis recommended
- Hepatotoxicity - monitor liver enzymes
- Severe cutaneous reactions - angioedema, SJS, TEN, DRESS
- Monitor for tumor lysis syndrome and tumor flare reaction
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.