Lipired 160

• Hyperlipidemia (Type IIa, IIb, III, IV and V): Indicated for patients who have not responded adequately to diet and other appropriate measures.
• High Triglycerides: Used for lowering triglyceride levels.
• High Cholesterol: Used for lowering total cholesterol and LDL cholesterol.

Fenofibrate is a fibric acid derivative. Fenofibrate is rapidly hydrolyzed after oral ingestion to its pharmacologically active form, fenofibric acid. Fenofibric acid produces reductions in total cholesterol, LDL cholesterol, Apo-lipoprotein B, Total triglycerides and VLDL. In addition, treatment with Fenofibrate results in increases in HDL and apo-proteins apoAI apoAII.

Adult Dose (Oral):

• Hypercholesterolemia, Mixed Dyslipidemia: Tablet: 40-160 mg once daily; Capsule: 200 mg once daily.
• Hypertriglyceridemia: 67-200 mg/day.

Child Dose: Safety and efficacy not established.

Common Side Effects:

• Increased liver enzymes
• Nausea
• Vomiting
• Flatulence
• Abdominal pain
• Diarrhea
• Headache
• Dizziness
• Fatigue
• Hair loss

Use in Pregnancy: Fenofibrate may be unsafe; animal studies have shown harmful effects on the developing baby.

Precautions:

• Fenofibrate does not usually affect your ability to drive.
• Take with food.
• Avoid alcohol consumption.
• Your doctor may check your liver function before starting treatment and regularly thereafter.
• Notify your doctor if you are more tired than usual, do not feel hungry, or if you have yellow eyes, skin or dark urine.
• Inform doctor if you experience muscle pain, tenderness, cramps, or weakness (especially with fever).
• Do not discontinue Fenofibrate without consulting your doctor even if you feel better.
• Renal impairment: dose adjustment may be needed; severe renal impairment: not recommended.

Overdose: No specific treatment for overdose; general supportive care indicated.

Storage: Do not store above 30 degree C. Keep away from light and out of reach of children.