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Ursodeoxycholic Acid is a medicine used to dissolve certain types of gallstones, to prevent them from forming and to treat a type of liver disease called primary biliary cirrhosis. It is a bile acid which helps break down cholesterol which has formed into stones in your gallbladder. Ursodeoxycholic Acid should be taken after a meal with a glass of milk or water. The dose will depend on what you are being treated for and your body weight. It would be best to swallow it whole. This medicine needs to be taken regularly to get the most benefit and you may have to take it for several months or longer, so try to get into a routine. Keep using it as prescribed even if your symptoms disappear. Even if the gallstones completely dissolve, the treatment should still be continued for several weeks or months. The most common side effects are diarrhea, stomach upset or pain, nausea, dizziness, back pain or hair loss. Not everyone gets side effects. If you are worried about them, or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment. Before taking this medicine, you should tell your doctor if you have an inflammation of the gallbladder or bile ducts, you get frequent cramp-like pain in your upper abdomen, you have been coughing up blood or you have gained weight rapidly. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor all other medicines you are taking. Women who use this medicine for dissolving gallstones should stop using the birth control pill because the hormones present in it can increase the production of gallstones. During the treatment, you may need ultrasound scans, or frequent blood tests to check your liver function. Ursodeoxycholic Acid is a hepatoprotective medication. It works by reducing the amount of cholesterol in the blood and helps dissolve gallbladder stones that are composed mainly of cholesterol. It also improves liver enzymes, protects liver cells from injury caused due to toxic bile acids, and improves liver function.

• Primary biliary cirrhosis • Gallbladder stones

Ursodeoxycholic acid suppresses hepatic synthesis and secretion of cholesterol and also inhibits intestinal absorption of cholesterol.

Adult Dose: Oral Dissolution of cholesterol-rich gallstones Adult: 8-12 mg/kg once daily at bedtime or in 2 divided doses continued for 3-4 mth after radiological disappearance of gallstones. Duration of treatment: Up to 2 yr. Obese patients: Up to 15 mg/kg daily. Primary biliary cirrhosis Adult: 10-16 mg/kg daily in 2-4 divided doses, may be taken once daily in the evening after the 1st 3 mth. Prophylaxis of gallstones in patients undergoing rapid weight loss Adult: 300 mg bid. Non-alcoholic fatty liver disease: 13-15 mg/kg/day;

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ursodeoxycholic Acid is to be taken with food.

If you miss a dose of Ursodeoxycholic Acid, skip it and continue with your normal schedule. Do not double the dose.

Common: • Abdominal pain • Diarrhea • Hair loss • Itching • Nausea • Rash

[SAFE] Ursodeoxycholic Acid does not usually affect your ability to drive. Ursodeoxycholic Acid should be taken after a meal with a glass of milk or water. Eat a healthy diet, exercise regularly and avoid alcohol intake. Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools. Your doctor may monitor your liver function and bilirubin levels every month for next 3 months after the start of therapy, and every 6 months thereafter. Do not stop taking the medication without talking to your doctor.

Acute inflammation of gallbladder or biliary tract, occlusion of biliary tract, frequent episodes of biliary colic, radio-opaque calcified gallstones, impaired contractility of gallbladder, non-functioning gallbladder, inflammatory bowel disease, hepatic and intestinal conditions interfering w/ enterohepatic recirculation of bile acids, extrahepatic and intrahepatic cholestasis, ileal resection and stoma, regional ileitis, active duodenal and gastric ulcer; acute, chronic or severe hepatic disease.

Cholestyramine, charcoal and antacids may reduce effectiveness. Aluminum-based antacids may reduce absorption. Oestrogens and clofibrate may counteract effectiveness of ursodeoxycholic acid by increasing cholesterol elimination in bile. Possible increase in ciclosporin serum concentration. Decreased effectiveness of dapsone. Possible decrease in serum ciprofloxacin and nitrendipine.

[UNSAFE] Ursodeoxycholic Acid may cause excessive drowsiness with alcohol.

[SAFE IF PRESCRIBED] Ursodeoxycholic Acid is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

[SAFE IF PRESCRIBED] Ursodeoxycholic Acid is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

[CONSULT YOUR DOCTOR] There is limited information available on the use of Ursodeoxycholic Acid in patients with kidney disease. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Ursodeoxycholic Acid in patients with liver disease. Please consult your doctor.

Good evening mam my self v.k tiwari(MD) i fill the patient information. Age she is my regular patient shi hafe second trimester of pregnancy is suffering from jaundice(SGPT 350) serum bilirubin 4.6 my frist prescription was iv D5% with inj LORNIT10 ML+inj vit k(im) od for 7 days acute treatment and chronic treatment was tab LIVERIL od syp LIV52 tds and powder glucose 150gm daily in divided dose can you please sugges me these all drugs are safe for second trimester of pregnancy Yes they are safe.also add udiliv 300 mg twice a day I have a small pieces of stones in galblader, the doctor advice me to take Udiliv 300 mg, Is this medicene remove the stones from gallbladder is this medicene good for rmoving the stoe laparoscopic surgery is preferred. I don't prescribe any medicine for gallstone since they are not effective Can I use udiliv300 in high cholesterol and minor chest pain Udiliv not for d purpose get Tmt done My Spot and Sgpt Level are around 130 each. I had a history of drinking . Now I Had quit it from about 20 Days. Also taking udiliv 300 tab twice a day. How long will it take to get result normal Alcoholic liver disease has three stages fatty liver, hepatitis n cirrhosis. Only the first stage is reversible. To know your status I need to know your PT, INR level, Complete LFT, HbA1c, ultrasound liver & biliary system with spleen size n size of portal vein from a qualified radiologist who is MD radiology and not less than that.Your sgot n pt values may be high because of fatty liver as well as I see you are 99kgs.Please get your lipid profile(F) alongwith other tests n take an appointment with meFor online consultation @lybrate app. Or www.lybrate.com I've a gall stone. By ultrasound a calculas ( 1.43 cm) is seen in lumen. I'm taking udiliv 300 mg for last 2 months. After taking this medicine I'm feeling better now. I've no problem now. No pain. No acidity. Nothing. Does it effective? Can it dissolve my stone? Plz ans. Stone needs surgical removalUdiliv does not help in stone removal He has a stone in galbladder of size 0.43 cm. Ha had taken udiliv 150 half tablet twice (morning and evening) for 3 months, but 3 months scan no change in size. Dear sir usually gall stones do no respond to medicines. but there are some medicine which can be tried, but their outcome is not sure I am 8month pregnant I am suffering from itching problem in my palm and foot mostly and full body itching Doctor prescribed me to test serum bilirubin and one more test gtvt ( liver test) results of serum bilirubin is normal but gtvt is 169 What should I take medicines in itching problem Udiliv 300mg twice a day till delivery. Do not worry it is safe in pregnancy What medicine we should take in jaundice during pregnancy ? I am taking Udiliv 300 tab last 25 days but the bilirubin is 2.53 as pathology report. Consult personally please Cause of jaundice needs to be ascertained