৳ 1/unit
Pack: ৳ 1
৳ 1/unit
Pack: ৳ 1
At a glance
Ursodeoxycholic Acid is used to dissolve certain types of gallstones, to prevent them from forming, and to treat a type of liver disease called primary biliary cirrhosis. It is a bile acid which helps break down cholesterol which has formed into stones in your gallbladder.
Indications
- Cholestasis (Jaundice)
- Viral Hepatitis
- Alcoholic Fatty Liver
- Primary Biliary Cirrhosis (PBC)
- Primary Sclerosing Cholangitis (PSC)
- Dissolution of Gallstones
- Non-Alcoholic Steatohepatitis (NASH)
- Gallbladder stones
Pharmacology
Ursodeoxycholic Acid is a naturally occurring bile acid used to treat different hepatobiliary disorders. The activity is achieved through a decrease in secretion of cholesterol in bile. It reduces cholesterol absorption, suppresses liver cholesterol synthesis, and does not inhibit bile acid synthesis.
Dosage
Adult Dose (Oral):
- Dissolution of cholesterol-rich gallstones: 8-12 mg/kg once daily at bedtime or in 2 divided doses; continue for 3-4 months after radiological disappearance; duration up to 2 years
- Primary biliary cirrhosis: 10-16 mg/kg daily in 2-4 divided doses
- Prophylaxis of gallstones in rapid weight loss: 300 mg twice daily
- Non-alcoholic fatty liver disease: 13-15 mg/kg/day
Side effects
Common Side Effects:
- Abdominal pain
- Diarrhea
- Hair loss
- Itching
- Nausea
- Rash
- Vomiting
Use in pregnancy
Use in Pregnancy: Generally considered safe; animal studies show low or no adverse effects; consult your doctor.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Does not usually affect ability to drive
- Take after a meal with a glass of milk or water
- Eat a healthy diet, exercise regularly, and avoid alcohol
- Diarrhea may occur; drink plenty of fluids and inform doctor if persistent
- Liver function and bilirubin levels may be monitored regularly
- Do not stop medication without talking to your doctor
Overdose effects
Symptoms: Diarrhea, nausea, vomiting.
Treatment: Supportive care.
Storage conditions
Store below 25°C. Protect from light and moisture. Keep out of reach of children.