Maxlev500mg
Rx- Generic:
- Levofloxacin
- Company:
- Novus Pharmaceuticals Ltd.
- Dosage form:
- Tablet
- Pack size:
- Tablet
৳ 1/unit
Pack: ৳ 1
At a glance
Levofloxacin — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Levofloxacin is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, skin and soft tissues and lungs (pneumonia). It cures the infection by stopping the further growth of the causative microorganisms. Levofloxacin should be used in the dose and duration as advised by your doctor. It may be taken with or without food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned. You may have a headache, dizziness, nausea, and constipation as side effects of this medicine. These are usually temporary and resolves on its own, but please consult your doctor if it bothers you or persists for a longer duration. Diarrhea may also occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools. You should not take this medicine if you are allergic to any of its ingredients. Special care should be taken in people with kidney problems while taking this medicine. Levofloxacin is an antibiotic. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.
Indications
• Bacterial infections
Mechanism of action
Levofloxacin exerts antibacterial action by inhibiting bacterial topoisomerase IV and DNA gyrase, the enzymes required for DNA replication, transcription repair and recombination. It has in vitro activity against a wide range of gram-negative and gram-positive microorganisms.
Dosage
Adult Dose: Community-Acquired Pneumonia 500 mg PO/IV once daily for 7-14 days or 750 mg PO/IV once daily for 5 days Nosocomial Pneumonia 750 mg PO/IV once daily for 7-14 days Acute Bacterial Sinusitis 500 mg PO/IV once daily for 10-14 days or 750 mg PO/IV once daily for 5 days Limitations-of-use: Reserve fluoroquinolones for patients who do not have other available treatment options for acute sinusitis Acute Bacterial Exacerbation of Chronic Bronchitis 500 mg PO/IV once daily for 7 days Limitations-of-use: Reserve fluoroquinolones for patients who do not have other available treatment options for acute bacterial exacerbation of chronic bronchitis Inhalational Anthrax Postexposure therapy 500 mg PO once daily for 60 days, beginning as soon as possible after exposure Skin/Skin Structure Infections Uncomplicated: 500 mg PO/IV once daily for 7-10 days Complicated: 750 mg PO/IV once daily for 7-14 days Chronic Bacterial Prostatitis 500 mg PO/IV once daily for 28 days Complicated Urinary Tract Infections & Acute Pyelonephritis 250 mg PO/IV once daily for 10 days or 750 mg PO/IV once daily for 5 days Uncomplicated Urinary Tract Infections 250 mg PO/IV once daily for 3 days Limitations-of-use: Reserve fluoroquinolones for patients who do not have other available treatment options for uncomplicated urinary tract infections Plague Indicated for treatment and prophylaxis of plague, including pneumonic and septicemic plague, caused by Yersinia pestis in adults and pediatric patients, aged 6 months or older 500 mg PO/IV once daily for 10-14 days Child Dose: Children PO, IV 16 mg/kg/day div q12h up to 50 kg body weight, then 500 mg qd for postexposure anthrax prophylaxis q12h For respiratory infections: 5 y: 10 mg/kg/day q24h Renal Dose: Renal impairment: Haemodialysis/CAPD: Initially, 500 mg daily, then 250 mg every 48 hr. Alternatively: Initially, 750 mg daily, then 500 mg every 48 hr. CrCl (ml/min) 20-49 Initially, 500 mg daily, then 250 mg every 24 hr. Alternatively: Initially, 750 mg daily, then 750 mg every 48 hr. 10-19 Initially, 500 mg daily, then 250 mg every 48 hr. Alternatively: Initially, 750 mg daily, then 500 mg every 48 hr.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Levofloxacin may be taken with or without food, but it is better to take it at a fixed time. Avoid Levofloxacin with dairy products such as milk, cheese, curd, butter, paneer and ice cream.
Missed dose
If you miss a dose of Levofloxacin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Headache • Dizziness • Nausea • Constipation • Diarrhea
Precautions & warnings
[UNSAFE] Levofloxacin may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Your doctor has prescribed Levofloxacin to cure your infection and improve symptoms. Do not skip any doses and finish the full course of treatment even if you feel better. Discontinue Levofloxacin and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing. Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools. Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations. Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Contraindications
Hypersensitivity to levofloxacin or other quinolones. Child <18 yr.
Drug interactions
Additive effects on QT interval prolongation w/ class IA (e.g. quinidine, procainamide) or class III (amiodarone, sotalol) antiarrhythmics, fluoxetine or imipramine. Reduced absorption w/ sucralfate, didanosine, antacids containing Mg or Al, dietary supplements containing Zn, Ca, Mg or Fe. Altered glucose levels w/ antidiabetic agents (e.g. insulin, glibenclamide). Increased risk of severe tendon disorders w/ corticosteroids. Increased risk of CNS stimulation and seizures w/ NSAIDs. Increased prothrombin time w/ warfarin.
Food interactions
[SAFE] Consuming alcohol with Levofloxacin does not cause any harmful side effects.
Use in pregnancy
[CONSULT YOUR DOCTOR] Levofloxacin is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Levofloxacin is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Renal / hepatic impairment
[CAUTION] Levofloxacin should be used with caution in patients with kidney disease. Dose adjustment of Levofloxacin may be needed. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Levofloxacin in patients with liver disease. Please consult your doctor. However, stop the medicine and inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.
Common questions
I am suffering before two months are very frequent urination and extreme irritation. Sir please tell me what i do? Start tablet levoflox.500 mg 1 tablet once a day for 5 days. Suffering from high grade fever since last three days. Fever is continuously in the range of 101 deg. Feeling slight cold, headache & body pain (not joint pain). tab levoflox 500 mg od for 5 days Sir what is the perfect curation of E-coli bacteria? report is attached with Take tab levoflox 500 once a day gor 14 days Continuious water from nose. sardi. head ache. please suggest good medicines I am studying inter first year. from Wednesday. final exams. Please suggest good medicines Take LCZ PLUS TWICE daily and levoflox 500 mg once daily for 5 days I m suffering with mild pain in left lower abdomen n burning sensation in urine along with pain. Get ultrasound KUB and urine culture done. Start tab levoflox 500 mg once a day for 3 days. Having cold and cough with irritaion in throat.allergic.to levoflox group of medicines.kindly advice other subsitute to levoflox group for throat pain relief Warm saline gargles and steam inhalation. For prescription medicine you need to visit a clinic I have a history of recurring yeast and bacterial vaginosis infections. Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days My rt side testical got swelled . I took levoflox but i didnt get full relief from medicine. Take tab covatil 500mg cv for five days