৳ 0.70/unit
Pack: ৳ 0.70
৳ 0.70/unit
Pack: ৳ 0.70
At a glance
Mebendazole is an antiparasitic medication used in the treatment of worm infections. It inhibits microtubule formation and prevents glucose and nutrient absorption, killing the worms.
Indications
- Threadworms (enterobiasis)
- Whipworms (trichuriasis)
- Roundworms (ascariasis)
- Hookworms (ancylostomiasis)
- Tapeworms (taeniasis)
- Strongyloidiasis
Pharmacology
Mebendazole inhibits microtubule formation in worms and prevents glucose and nutrient absorption, leading to glycogen depletion and worm death.
Dosage
Adult Dose (Oral):
- Threadworms: 100 mg (1 tablet or 1 teaspoonful suspension) single dose; repeat after 3 weeks if needed
- Roundworms/Hookworms/Whipworms: 100 mg twice daily for 3 days; repeat after 3 weeks if needed
- Tapeworms/Strongyloidiasis: 100 mg twice daily for 3 days
Children (>2 years): Adult dose
Side effects
Common Side Effects:
- Abdominal pain
- Diarrhea (with massive worm expulsion)
- Nausea
Rare:
- Skin rash, urticaria, angioedema
- Seizures (very rare)
- Neutropenia, agranulocytosis
Use in pregnancy
Use in Pregnancy: Mebendazole may be unsafe during pregnancy; animal studies have shown harmful effects on the fetus. Avoid use, especially during the first trimester.
Precautions & warnings
- Periodic assessment of hematopoietic and hepatic function during prolonged therapy
- Inform patients of potential risk to fetus, especially during first trimester
- Cleanliness is important to prevent reinfection and transmission
- Consult doctor during pregnancy and lactation
Overdose effects
Overdose may cause gastrointestinal complaints lasting up to a few hours; induce vomiting and purging.
Storage conditions
Store below 25°C in a cool and dry place, protected from light; keep out of reach of children.