osudhkosh

Megapime IV/IM2gm/vial

Rx
Generic:
Cefepime
Company:
Eskayef
Dosage form:
Injection
Pack size:
2gm vial
Save to my medicines
Alert me on price drop

৳ 1,100/unit

Pack: ৳ 1,100

Price comparison

This brand
1100
Cheapest of this genericZopime
1

The cheaper brand costs ৳ 1099.00 less per unit

Compared against 13 brands

At a glance

Cefepime is a 4th generation cephalosporin antibiotic used to treat severe bacterial infections of the skin, lungs, stomach, urinary tract, and blood.

Indications
  • Moderate to Severe Pneumonia
  • Febrile Neutropenia
  • Uncomplicated and Complicated Urinary Tract Infections (including pyelonephritis)
  • Uncomplicated Skin and Skin Structure Infections
  • Complicated Intra-abdominal Infections (used in combination with metronidazole)
Dosage

Adult Dose (IV):

Infection TypeDoseScheduleDuration
Urinary Tract Infection (UTI)0.5-1 g12 hourly7-10 days
Febrile Neutropenia (Empiric)2 g8 hourly7 days or until neutropenia resolves
Moderate to Severe Pneumonia1-2 g12 hourly10 days
Complicated Intra-abdominal (with metronidazole)2 g12 hourly7-10 days
Uncomplicated Skin & Skin Structure2 g12 hourly10 days

Pediatric Dose (2 months-16 years):

WeightInfection TypeDoseScheduleDuration
All weightsUTI, Skin, Pneumonia (Uncomplicated/Complicated)50 mg/kg/dose12 hourly7-10 days
<40 kgFebrile Neutropenia (Empiric)50 mg/kg/dose8 hourly7 days or until neutropenia resolves

Renal Dose Adjustment:

Creatinine Clearance (ml/min)DoseSchedule
30-600.5-2 g24 hourly
11-290.5-1 g24 hourly
<100.25-0.5 g24 hourly
HemodialysisDay 1: 1 g, then 0.5 g24 hourly (after dialysis)
CAPDAdult dose48 hourly
Side effects

Common Side Effects:

  • Rash
  • Itching
  • Nausea
  • Vomiting
  • Headache
  • Fever
  • Diarrhea
  • Abdominal pain
Precautions & warnings
  • [CONSULT YOUR DOCTOR] It is not known whether Cefepime alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
  • Your doctor has prescribed Cefepime to cure your infection and improve your symptoms. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
  • Discontinue Cefepime and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
  • Avoid consuming alcohol while taking Cefepime as it may cause increased side effects.
  • Prescribing Cefepime in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.
  • As with other antimicrobials, prolonged use of Cefepime may result in overgrowth of non susceptible microorganisms. Repeated evaluation of the patient's condition is essential.
  • Many cephalosporins, including cefepime, have been associated with a fall in prothrombin activity. Those at risk include patients with renal or hepatic impairment, or poor nutritional state, as well as patients receiving a protracted course of antimicrobial therapy. Prothrombin time should be monitored in patients at risk.
  • Cefepime should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis.
Cefepime — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.