Merozolyn5mg
Rx- Generic:
- Metolazone
- Dosage form:
- Tablet
- Pack size:
- Box (10 Tablet)
৳ 25/unit
Pack: ৳ 250
At a glance
Metolazone — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Metolazone is a type of diuretic (water pill) medicine. This medicine reduces excess fluid levels in the body and is used to treat edema (fluid overload) associated with heart, liver, kidney, or lung disease. It is also used in treatment of hypertension (high blood pressure). Metolazone makes you lose excess water through urine. It may be used alone or in combination with other medicines. This medicine should be taken only during day time to avoid frequent urination at night. You must take this medicine in the dose and duration as advised by the doctor and never stop it abruptly without consulting the doctor. Common side effects of this medicine include headache, nausea, and dizziness. Consult your doctor if these side effects bother you. Before taking this medicine, it is better to let your doctor know if you are suffering from any kidney or liver disease. Also, pregnant women and breastfeeding mothers should consult a doctor before taking it. You must inform the doctor about all the other medicines that you are taking apart from this medicine. Regular monitoring of kidney function and electrolytes is important while using this medicine. Metolazone is a thiazide diuretic. It lowers blood pressure and fluid retention in edema by removing the extra water and certain electrolytes from the body. Over time it also works by relaxing blood vessels and improving blood flow.
Indications
• Hypertension (high blood pressure)
Mechanism of action
Metolazone is a thiazide-like diuretic. It inhibits reabsorption of sodium in the distal tubules resulting in increased excretion of sodium and water, as well as potassium and hydrogen ions.
Dosage
Adult Dose: Oral Hypertension Adult: Initially, 1.25 mg daily, adjusted after 3-4 wk according to response. Usual dose: 2.5-5 mg daily, either alone or with other antihypertensives. Maintenance dose: 5 mg on alternate days. Formulations with enhanced bioavailability: 0.5-1 mg daily. Oedema Adult: 5-10 mg daily, increased if necessary to 20 mg daily. Max: 80 mg in 24 hr. Elderly: Initially, 2.5 mg/day or every other day. Child Dose: Oedema 0.2-0.4 mg/kg/day PO in single daily dose or divided q12hr Renal Dose: Renal impairment: Not necessary to supplement dose in hemodialysis or peritoneal dialysis
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metolazone is to be taken with food.
Missed dose
If you miss a dose of Metolazone, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Headache • Nausea • Increased blood uric acid • Decreased potassium level in blood • Glucose intolerance • Altered blood lipid level
Precautions & warnings
[UNSAFE] Metolazone may cause side effects which could affect your ability to drive. As Metolazone may cause drowsiness, dizziness, blurred vision, or lightheadedness and this may affect your ability to drive. Take it in the morning with breakfast to avoid getting up at night to urinate. It makes you feel dizzy. Avoid driving and attention requiring activity until you know how it affects you. Avoid alcohol intake while taking Metolazone as it may increase the dizziness. It may cause a sudden drop of sodium level in blood. Avoid low sodium diet while you are taking this medication. Monitor your blood pressure after starting Metolazone, and notify your doctor if it does not lower down. Notify your doctor if you experience dizziness, tiredness, or muscle weakness that does not go away. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Contraindications
Anuria; hepatic coma or pre-coma. Pregnancy.
Drug interactions
Hypotensive and nephrotoxic effects of ACE inhibitors may be enhanced. Absorption may be reduced with bile acid sequestrants. Hyperglycaemic effect may be enhanced with diazoxide. May increase serum concentration and QTc-prolonging effect of dofetilide. May reduce lithium excretion. Hypotensive effect may be increased with alcohol. Potentially Fatal: Increased risk of nephrotoxicity with ciclosporin. Severe electrolyte disturbances may occur with furosemide.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Metolazone.
Use in pregnancy
[SAFE IF PRESCRIBED] Metolazone is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Use in lactation
[SAFE IF PRESCRIBED] Metolazone is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Metolazone is safe to use in patients with kidney disease. No dose adjustment of Metolazone is recommended. [CONSULT YOUR DOCTOR] There is limited information available on the use of Metolazone in patients with liver disease. Please consult your doctor.
Common questions
I am a patient of hypertension Hypertension is clinal condition of high blood pressure. Please see a physician. Some times I had lot of hypertension Hypertension is clinically high blood pressure. Persistent high arterial blood pressure above 120/80 mm HG is termed as pre-hypertension or hypertension, but the point to be emphasized is that this rise in blood pressure is persistent. Transient increase in BP occurs in stress and anxiety and needs to be treated accordingly. High blood pressure, breathing issues Do yoga and pranayam regularly, take halleezy tablet 2 tablet twice Hypertension blood pressure pro Bp any medicine u taking Wait loss and high blood pressure Take medohar guggul 2 tab twice, vrikshamla tablet twice with water, do yoga and pranayam I'm type 2 diabetic patient with hypertension, l am taking following medicines Tezloc 40 - OD Glimisave Max-1 forte. BBF Glimisave Max-2 forte Cd Rozavel -5. Hs My usual blood pressure -80/145 Usual Blood glucose levels :fasting -120 PP-180 Hba1c - 7.6 Pl suggest me whether I need any change in medicines etc. I'm taking Januvia-100 also seems ok basically need control of blood pressure and hypertension get an ecg n echo done totally impotency due to diabetes and high blood pressure control ur sugars and b.ptake tablet dejac t 1 hr befr sex Which tablet is best for high blood pressure.I am taking telmisim 40 Which tablet is best for high blood pressure. I am taking telmisim 40 Depends on your blood pressure range kidney and heart functions