osudhkosh

Metalyse50mg

Rx
Generic:
Tenecteplase
Dosage form:
Injection
Pack size:
Injection
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৳ 64,500/unit

Pack: ৳ 64,500

At a glance

Tenecteplase is a fibrin-specific thrombolytic used for emergency treatment of acute myocardial infarction. It dissolves blood clots by converting plasminogen to plasmin.

Indications
  • Acute myocardial infarction (AMI)
Dosage

Adult Dose (IV):

  • Weight <60 kg: 30 mg
  • 60-<70 kg: 35 mg
  • 70-<80 kg: 40 mg
  • 80-<90 kg: 45 mg
  • ≥90 kg: 50 mg
  • Single IV bolus dose over 5 seconds – as soon as possible after symptom onset
Side effects

Most Common Side Effects:

  • Bleeding (most frequent)
  • Intracranial hemorrhage (0.9%)
  • Hematoma (12.3% minor; 1.7% major)
  • Gastrointestinal bleeding (1%)
  • Epistaxis (1.5%)
  • Nausea, vomiting, hypotension, fever
Precautions & warnings
  • Do not use in active internal bleeding, recent cerebrovascular accident, intracranial/intraspinal surgery or trauma within 2 months
  • Do not use in intracranial neoplasm, AV malformation or aneurysm, bleeding diathesis, severe uncontrolled hypertension
  • Minimize arterial and venous punctures
  • Discontinue heparin and antiplatelets in serious bleeding
Tenecteplase — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.